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    Polr3f polymerase (RNA) III (DNA directed) polypeptide F [ Mus musculus (house mouse) ]

    Gene ID: 70408, updated on 16-Jul-2021

    Summary

    Official Symbol
    Polr3fprovided by MGI
    Official Full Name
    polymerase (RNA) III (DNA directed) polypeptide Fprovided by MGI
    Primary source
    MGI:MGI:1924086
    See related
    Ensembl:ENSMUSG00000027427
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    RP; RPC; RPC6; RPC39; 2810411G20Rik; 3010019O03Rik; 3110032A07Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 5.5), CNS E14 (RPKM 4.5) and 25 other tissues See more
    Orthologs
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    Genomic context

    See Polr3f in Genome Data Viewer
    Location:
    2; 2 G1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (144369665..144383699)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (144527745..144541779)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (144353481..144367515)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene zinc finger protein 133, pseudogene Neighboring gene zinc finger protein 133, pseudogene Neighboring gene double zinc ribbon and ankyrin repeat domains 1 Neighboring gene retinoblastoma binding protein 9, serine hydrolase Neighboring gene predicted gene, 34292 Neighboring gene SEC23 homolog B, COPII coat complex component

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC11656

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-directed 5'-3' RNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within defense response to virus IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within immune system process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within innate immune response IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of innate immune response ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of interferon-beta production ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in transcription by RNA polymerase III IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of RNA polymerase III complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of RNA polymerase III complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    DNA-directed RNA polymerase III subunit RPC6
    Names
    DNA-directed RNA polymerase III subunit F
    RNA polymerase III subunit C6
    NP_084039.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029763.3NP_084039.2  DNA-directed RNA polymerase III subunit RPC6

      See identical proteins and their annotated locations for NP_084039.2

      Status: VALIDATED

      Source sequence(s)
      AK029286, AK036166
      Consensus CDS
      CCDS16820.1
      UniProtKB/Swiss-Prot
      Q921X6
      UniProtKB/TrEMBL
      Q8C108
      Related
      ENSMUSP00000028914.3, ENSMUST00000028914.9
      Conserved Domains (1) summary
      pfam05158
      Location:12315
      RNA_pol_Rpc34; RNA polymerase Rpc34 subunit

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      144369665..144383699
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_027417.1: Suppressed sequence

      Description
      NM_027417.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
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