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    Cox10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 10 [ Mus musculus (house mouse) ]

    Gene ID: 70383, updated on 4-Sep-2018

    Summary

    Official Symbol
    Cox10provided by MGI
    Official Full Name
    heme A:farnesyltransferase cytochrome c oxidase assembly factor 10provided by MGI
    Primary source
    MGI:MGI:1917633
    See related
    Ensembl:ENSMUSG00000042148 Vega:OTTMUSG00000005891
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AU042636; 2410004F01Rik
    Expression
    Ubiquitous expression in heart adult (RPKM 18.8), kidney adult (RPKM 13.0) and 28 other tissues See more
    Orthologs

    Genomic context

    See Cox10 in Genome Data Viewer
    Location:
    11; 11 B3
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (63962627..64079472, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (63776129..63892974, complement)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 Neighboring gene RIKEN cDNA 9630013K17 gene Neighboring gene predicted gene, 30060 Neighboring gene RIKEN cDNA 2810001G20 gene Neighboring gene predicted gene 12290

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    contributes_to cytochrome-c oxidase activity ISO
    Inferred from Sequence Orthology
    more info
     
    farnesyltranstransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    protoheme IX farnesyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity, transferring alkyl or aryl (other than methyl) groups IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    aerobic respiration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular respiration IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cellular respiration ISO
    Inferred from Sequence Orthology
    more info
     
    cytochrome complex assembly IDA
    Inferred from Direct Assay
    more info
    PubMed 
    heme O biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    heme a biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    heme a biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    heme a biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    heme biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrial fission IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitochondrion organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein farnesylation ISO
    Inferred from Sequence Orthology
    more info
     
    respiratory chain complex IV assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytochrome complex ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrial membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion HDA PubMed 
    mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    protoheme IX farnesyltransferase, mitochondrial
    Names
    COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase
    cytochrome c oxidase assembly protein 10
    heme O synthase
    NP_848466.1
    XP_006534231.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178379.3NP_848466.1  protoheme IX farnesyltransferase, mitochondrial

      See identical proteins and their annotated locations for NP_848466.1

      Status: VALIDATED

      Source sequence(s)
      AK149999, AL603889, BY078593
      Consensus CDS
      CCDS24839.1
      UniProtKB/Swiss-Prot
      Q8CFY5
      UniProtKB/TrEMBL
      Q3U3N1, Q3UDN4
      Related
      ENSMUSP00000040138.8, OTTMUSP00000006085, ENSMUST00000049091.8, OTTMUST00000013112
      Conserved Domains (1) summary
      cd13957
      Location:159414
      PT_UbiA_Cox10; Protoheme IX farnesyltransferase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      63962627..64079472 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006534168.3XP_006534231.1  protoheme IX farnesyltransferase, mitochondrial isoform X1

      Conserved Domains (1) summary
      cd13957
      Location:1198
      PT_UbiA_Cox10; Protoheme IX farnesyltransferase
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