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    Mospd1 motile sperm domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 70380, updated on 26-Sep-2022

    Summary

    Official Symbol
    Mospd1provided by MGI
    Official Full Name
    motile sperm domain containing 1provided by MGI
    Primary source
    MGI:MGI:1917630
    See related
    Ensembl:ENSMUSG00000023074 AllianceGenome:MGI:1917630
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1810018L05Rik
    Summary
    Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Located in nucleus and perinuclear region of cytoplasm. Is expressed in several structures, including brain; cranial ganglion; limb mesenchyme; tongue muscle; and vertebral axis musculature. Orthologous to human MOSPD1 (motile sperm domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in placenta adult (RPKM 12.9), liver E14 (RPKM 6.9) and 19 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Mospd1 in Genome Data Viewer
    Location:
    X; X A5
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (52433471..52459567, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (53344594..53370658, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 122, member B Neighboring gene family with sequence similarity 122, member C Neighboring gene ribosomal protein L13 pseudogene Neighboring gene casein kinase 1, gamma 3 pseudogene Neighboring gene embryonic testis differentiation

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    General gene information

    Homology

    Clone Names

    • MGC103065

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    motile sperm domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001290514.1NP_001277443.1  motile sperm domain-containing protein 1 isoform 2

      See identical proteins and their annotated locations for NP_001277443.1

      Status: VALIDATED

      Source sequence(s)
      AK139795, BF467665, BG068741, BG077592, CJ046213, DV651027
      Consensus CDS
      CCDS72381.1
      UniProtKB/Swiss-Prot
      Q8VEL0, Q9D8Y9
      UniProtKB/TrEMBL
      A0A6P5NZ28, Q3UT40
      Related
      ENSMUSP00000094182.3, ENSMUST00000096447.9
      Conserved Domains (1) summary
      pfam00635
      Location:16113
      Motile_Sperm; MSP (Major sperm protein) domain
    2. NM_001358456.1NP_001345385.1  motile sperm domain-containing protein 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      BG077592, BX679674
      Conserved Domains (1) summary
      pfam00635
      Location:16113
      Motile_Sperm; MSP (Major sperm protein) domain
    3. NM_027409.5NP_081685.1  motile sperm domain-containing protein 1 isoform 1

      See identical proteins and their annotated locations for NP_081685.1

      Status: VALIDATED

      Source sequence(s)
      AK007533, BF467665, BG068741, BG077592, CJ046213, DV651027
      Consensus CDS
      CCDS30131.1
      UniProtKB/Swiss-Prot
      Q8VEL0
      UniProtKB/TrEMBL
      A0A8C6H4G8
      Related
      ENSMUSP00000023836.4, ENSMUST00000023836.4
      Conserved Domains (1) summary
      pfam00635
      Location:16113
      Motile_Sperm; MSP (Major sperm protein) domain

    RNA

    1. NR_110964.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      BC085100, BG077592, CJ046213

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      52433471..52459567 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006541541.5XP_006541604.1  motile sperm domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A6P7QRZ3
      Conserved Domains (1) summary
      pfam00635
      Location:16113
      Motile_Sperm; MSP (Major sperm protein) domain
    2. XM_006541538.4XP_006541601.1  motile sperm domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006541601.1

      Conserved Domains (1) summary
      pfam00635
      Location:16113
      Motile_Sperm; MSP (Major sperm protein) domain
    3. XM_011251017.3XP_011249319.1  motile sperm domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011249319.1

      Conserved Domains (1) summary
      pfam00635
      Location:16113
      Motile_Sperm; MSP (Major sperm protein) domain
    4. XM_030251496.2XP_030107356.1  motile sperm domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A6P7QRZ3
      Conserved Domains (1) summary
      pfam00635
      Location:16113
      Motile_Sperm; MSP (Major sperm protein) domain
    5. XM_036162092.1XP_036017985.1  motile sperm domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A6P7QRZ3
      Conserved Domains (1) summary
      pfam00635
      Location:16113
      Motile_Sperm; MSP (Major sperm protein) domain
    6. XM_006541540.4XP_006541603.1  motile sperm domain-containing protein 1 isoform X2

      See identical proteins and their annotated locations for XP_006541603.1

      UniProtKB/Swiss-Prot
      Q8VEL0, Q9D8Y9
      UniProtKB/TrEMBL
      A0A6P5NZ28
      Conserved Domains (1) summary
      pfam00635
      Location:16113
      Motile_Sperm; MSP (Major sperm protein) domain
    7. XM_017318617.2XP_017174106.1  motile sperm domain-containing protein 1 isoform X2

      UniProtKB/Swiss-Prot
      Q8VEL0, Q9D8Y9
      UniProtKB/TrEMBL
      A0A6P5NZ28
      Conserved Domains (1) summary
      pfam00635
      Location:16113
      Motile_Sperm; MSP (Major sperm protein) domain

    RNA

    1. XR_004940365.1 RNA Sequence