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    Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 [ Mus musculus (house mouse) ]

    Gene ID: 70316, updated on 12-Aug-2018

    Summary

    Official Symbol
    Ndufab1provided by MGI
    Official Full Name
    NADH:ubiquinone oxidoreductase subunit AB1provided by MGI
    Primary source
    MGI:MGI:1917566
    See related
    Ensembl:ENSMUSG00000030869 Vega:OTTMUSG00000026510
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ACP; 8kDa; SDAP; CI-SDAP; 2210401F17Rik; 2310039H15Rik; 2610003B19Rik; 9130423F15Rik
    Expression
    Broad expression in adrenal adult (RPKM 768.6), duodenum adult (RPKM 586.0) and 16 other tissues See more
    Orthologs

    Genomic context

    See Ndufab1 in Genome Data Viewer
    Location:
    7; 7 F2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (122088044..122101876, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (129231558..129245362, complement)

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene glutamyl-tRNA synthetase 2, mitochondrial Neighboring gene ubiquitin family domain containing 1 Neighboring gene partner and localizer of BRCA2 Neighboring gene predicted gene 16326 Neighboring gene dynactin 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    acyl binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acyl carrier activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    phosphopantetheine binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    fatty acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    fatty acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    lipid A biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrial respiratory chain complex I assembly ISO
    Inferred from Sequence Orthology
    more info
     
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    protein lipoylation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    colocalizes_with mitochondrial large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrial respiratory chain complex I ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion HDA PubMed 
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    respiratory chain IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    acyl carrier protein, mitochondrial
    Names
    NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1
    NADH-ubiquinone oxidoreductase 9.6 kDa subunit

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360743.1NP_001347672.1  acyl carrier protein, mitochondrial precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Variants 1, 2, and 3 all encode the same protein.
      Source sequence(s)
      AC124379, BF019966
      Conserved Domains (1) summary
      cl09936
      Location:66152
      PP-binding; Phosphopantetheine attachment site
    2. NM_001360744.1NP_001347673.1  acyl carrier protein, mitochondrial precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 3' UTR compared to variant 1. Variants 1, 2, and 3 all encode the same protein.
      Source sequence(s)
      AC124379, AK010307
      Conserved Domains (1) summary
      cl09936
      Location:66152
      PP-binding; Phosphopantetheine attachment site
    3. NM_028177.4NP_082453.2  acyl carrier protein, mitochondrial precursor

      See identical proteins and their annotated locations for NP_082453.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, and 3 all encode the same protein.
      Source sequence(s)
      AC124379, AK011302
      Consensus CDS
      CCDS21809.1
      UniProtKB/Swiss-Prot
      Q9CR21
      UniProtKB/TrEMBL
      Q569N0
      Related
      ENSMUSP00000033157.3, OTTMUSP00000032702, ENSMUST00000033157.9
      Conserved Domains (1) summary
      cl09936
      Location:66152
      PP-binding; Phosphopantetheine attachment site

    RNA

    1. NR_153798.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks an alternate exon and differs in the 3' end compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC124379

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

      Range
      122088044..122101876 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006508200.3XP_006508263.1  acyl carrier protein, mitochondrial isoform X1

      UniProtKB/Swiss-Prot
      Q9CR21
      UniProtKB/TrEMBL
      Q569N0
      Related
      ENSMUSP00000116177.1, OTTMUSP00000032703, ENSMUST00000123296.7, OTTMUST00000065585
      Conserved Domains (1) summary
      cl09936
      Location:66152
      PP-binding; Phosphopantetheine attachment site
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