Format

Send to:

Choose Destination
    • Showing Current items.

    Poc1a POC1 centriolar protein A [ Mus musculus (house mouse) ]

    Gene ID: 70235, updated on 5-Aug-2018

    Summary

    Official Symbol
    Poc1aprovided by MGI
    Official Full Name
    POC1 centriolar protein Aprovided by MGI
    Primary source
    MGI:MGI:1917485
    See related
    Ensembl:ENSMUSG00000023345 Vega:OTTMUSG00000049423
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    cha; Wdr51a; 2510040D07Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 26.3), liver E14.5 (RPKM 10.9) and 25 other tissues See more
    Orthologs

    Genomic context

    See Poc1a in Genome Data Viewer
    Location:
    9; 9 F1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (106281022..106349891)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (106183392..106252222)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930500F10 gene Neighboring gene predicted gene, 33564 Neighboring gene dual specificity phosphatase 7 Neighboring gene predicted gene, 33616 Neighboring gene predicted gene, 46131

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Spontaneous (1)  1 citation
    • Targeted (2) 
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    bone development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell projection organization IEA
    Inferred from Electronic Annotation
    more info
     
    growth plate cartilage chondrocyte development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitotic spindle organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    non-motile cilium assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of centrosome duplication IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    spermatogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    centriole ISO
    Inferred from Sequence Orthology
    more info
     
    centrosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    spindle pole ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    POC1 centriolar protein homolog A
    Names
    WD repeat domain 51A
    WD repeat-containing protein 51A

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027354.2NP_081630.2  POC1 centriolar protein homolog A

      See identical proteins and their annotated locations for NP_081630.2

      Status: VALIDATED

      Source sequence(s)
      AK011064, BB234823, BE981233, CA557124, CD549942
      Consensus CDS
      CCDS23474.1
      UniProtKB/Swiss-Prot
      Q8JZX3
      Related
      ENSMUSP00000072064.6, OTTMUSP00000068183, ENSMUST00000072206.13, OTTMUST00000125993
      Conserved Domains (3) summary
      COG2319
      Location:13301
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:11299
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:2359
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      106281022..106349891
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006511830.3XP_006511893.1  POC1 centriolar protein homolog A isoform X1

      Conserved Domains (4) summary
      COG2319
      Location:15365
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:11299
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:2359
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:263365
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    2. XM_006511831.3XP_006511894.1  POC1 centriolar protein homolog A isoform X2

      Related
      ENSMUSP00000149262.1, OTTMUSP00000079863, ENSMUST00000214208.1, OTTMUST00000154486
      Conserved Domains (3) summary
      COG2319
      Location:13301
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:11299
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:2359
      7WD40; WD40 repeat [structural motif]
    Support Center