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    Cd2bp2 CD2 cytoplasmic tail binding protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 70233, updated on 12-Mar-2019

    Summary

    Official Symbol
    Cd2bp2provided by MGI
    Official Full Name
    CD2 cytoplasmic tail binding protein 2provided by MGI
    Primary source
    MGI:MGI:1917483
    See related
    Ensembl:ENSMUSG00000042502
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AW048183; 1500011B02Rik; 2410024K20Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 29.7), CNS E14 (RPKM 25.4) and 28 other tissues See more
    Orthologs

    Genomic context

    See Cd2bp2 in Genome Data Viewer
    Location:
    7; 7 F3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (127191660..127196077, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (134335174..134339514, complement)

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene sialophorin Neighboring gene TAR (HIV) RNA binding protein 2 pseudogene Neighboring gene TBC1 domain family, member 10b Neighboring gene myosin light chain, phosphorylatable, fast skeletal muscle

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ribonucleoprotein complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    U5 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    U5 snRNP ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    fibrillar center ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    CD2 antigen cytoplasmic tail-binding protein 2
    Names
    CD2 antigen (cytoplasmic tail) binding protein 2
    CD2 cytoplasmic domain-binding protein 2
    CD2 tail-binding protein 2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001285905.1NP_001272834.1  CD2 antigen cytoplasmic tail-binding protein 2

      See identical proteins and their annotated locations for NP_001272834.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-5 encode the same protein.
      Source sequence(s)
      AC122537, AK034689, BM944739
      Consensus CDS
      CCDS21859.1
      UniProtKB/Swiss-Prot
      Q9CWK3
      Related
      ENSMUSP00000145888.1, ENSMUST00000205316.1
      Conserved Domains (1) summary
      smart00444
      Location:282339
      GYF; Contains conserved Gly-Tyr-Phe residues
    2. NM_001285906.1NP_001272835.1  CD2 antigen cytoplasmic tail-binding protein 2

      See identical proteins and their annotated locations for NP_001272835.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-5 encode the same protein.
      Source sequence(s)
      AC122537, AK030393, AK034689
      Consensus CDS
      CCDS21859.1
      UniProtKB/Swiss-Prot
      Q9CWK3
      Related
      ENSMUSP00000146167.1, ENSMUST00000206026.1
      Conserved Domains (1) summary
      smart00444
      Location:282339
      GYF; Contains conserved Gly-Tyr-Phe residues
    3. NM_001285907.1NP_001272836.1  CD2 antigen cytoplasmic tail-binding protein 2

      See identical proteins and their annotated locations for NP_001272836.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1-5 encode the same protein.
      Source sequence(s)
      AC122537, AK034689, AK167249
      Consensus CDS
      CCDS21859.1
      UniProtKB/Swiss-Prot
      Q9CWK3
      Related
      ENSMUSP00000044790.3, ENSMUST00000035771.4
      Conserved Domains (1) summary
      smart00444
      Location:282339
      GYF; Contains conserved Gly-Tyr-Phe residues
    4. NM_001357817.1NP_001344746.1  CD2 antigen cytoplasmic tail-binding protein 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1-5 encode the same protein.
      Source sequence(s)
      AC122537
      Conserved Domains (1) summary
      smart00444
      Location:282339
      GYF; Contains conserved Gly-Tyr-Phe residues
    5. NM_027353.4NP_081629.1  CD2 antigen cytoplasmic tail-binding protein 2

      See identical proteins and their annotated locations for NP_081629.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-5 encode the same protein.
      Source sequence(s)
      AC122537, AK034689
      Consensus CDS
      CCDS21859.1
      UniProtKB/Swiss-Prot
      Q9CWK3
      Related
      ENSMUSP00000132963.1, ENSMUST00000166791.7
      Conserved Domains (1) summary
      smart00444
      Location:282339
      GYF; Contains conserved Gly-Tyr-Phe residues

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

      Range
      127191660..127196077 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006508197.2XP_006508260.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q9CWK3
      Conserved Domains (1) summary
      smart00444
      Location:282339
      GYF; Contains conserved Gly-Tyr-Phe residues
    2. XM_006508198.3XP_006508261.1  CD2 antigen cytoplasmic tail-binding protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006508261.1

      UniProtKB/Swiss-Prot
      Q9CWK3
      Conserved Domains (1) summary
      smart00444
      Location:282339
      GYF; Contains conserved Gly-Tyr-Phe residues
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