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    Dpf3 D4, zinc and double PHD fingers, family 3 [ Mus musculus (house mouse) ]

    Gene ID: 70127, updated on 31-Aug-2021

    Summary

    Official Symbol
    Dpf3provided by MGI
    Official Full Name
    D4, zinc and double PHD fingers, family 3provided by MGI
    Primary source
    MGI:MGI:1917377
    See related
    Ensembl:ENSMUSG00000021221
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CERD; CERD4; cer-d; BAF45C; C78788; cer-d4; Gm18872; 2810403B03Rik; 6530402L11Rik
    Expression
    Broad expression in testis adult (RPKM 4.7), cerebellum adult (RPKM 3.8) and 24 other tissues See more
    Orthologs
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    Genomic context

    See Dpf3 in Genome Data Viewer
    Location:
    12; 12 D1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (83260525..83534510, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (83213751..83487736, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (84370185..84451885, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene regulator of G-protein signaling 6 Neighboring gene predicted gene, 51988 Neighboring gene predicted gene, 53731 Neighboring gene DDB1 and CUL4 associated factor 4 Neighboring gene zinc finger, FYVE domain containing 1 Neighboring gene H2A histone family, member Z pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within chromatin organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of transcription, DNA-templated IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in nervous system development IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in nervous system development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of nBAF complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of nBAF complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    zinc finger protein DPF3
    Names
    BRG1-associated factor 45C
    D4 zinc and double PHD finger family 3
    cerebellum D4
    zinc finger protein cer-d4

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001267625.1NP_001254554.1  zinc finger protein DPF3 isoform 1

      See identical proteins and their annotated locations for NP_001254554.1

      Status: VALIDATED

      Source sequence(s)
      AK012970, AK039011
      Consensus CDS
      CCDS59574.1
      UniProtKB/Swiss-Prot
      P58269
      Related
      ENSMUSP00000136280.2, ENSMUST00000178756.8
      Conserved Domains (4) summary
      COG5189
      Location:195222
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      cd15530
      Location:318363
      PHD2_d4; PHD finger 2 found in d4 gene family proteins
      cd15692
      Location:261317
      PHD1_DPF3; PHD finger 1 found in D4, zinc and double PHD fingers family 3 (DPF3)
      pfam14051
      Location:1384
      Requiem_N; N-terminal domain of DPF2/REQ
    2. NM_001267626.2NP_001254555.1  zinc finger protein DPF3 isoform 2

      See identical proteins and their annotated locations for NP_001254555.1

      Status: VALIDATED

      Source sequence(s)
      AC139382, AC205767, CT025545
      UniProtKB/TrEMBL
      B5TZD5
      Related
      ENSMUSP00000122004.2, ENSMUST00000144237.8
      Conserved Domains (2) summary
      pfam14051
      Location:1384
      Requiem_N; N-terminal domain of DPF2/REQ
      cl22851
      Location:261292
      PHD_SF; PHD finger superfamily
    3. NM_058212.3NP_478119.1  zinc finger protein DPF3 isoform 3

      See identical proteins and their annotated locations for NP_478119.1

      Status: VALIDATED

      Source sequence(s)
      AC139382, AC205767, CT025545
      Consensus CDS
      CCDS56846.1
      UniProtKB/Swiss-Prot
      P58269
      Related
      ENSMUSP00000137477.2, ENSMUST00000177959.8
      Conserved Domains (2) summary
      pfam14051
      Location:1384
      Requiem_N; N-terminal domain of DPF2/REQ
      cl22851
      Location:260291
      PHD_SF; PHD finger superfamily

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      83260525..83534510 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    2. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      83316202..83341274 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_018261.2: Suppressed sequence

      Description
      NG_018261.2: This RefSeq was removed because it is now thought that this gene does encode a protein.
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