Format

Send to:

Choose Destination
    • Showing Current items.

    Cep85 centrosomal protein 85 [ Mus musculus (house mouse) ]

    Gene ID: 70012, updated on 8-Aug-2021

    Summary

    Official Symbol
    Cep85provided by MGI
    Official Full Name
    centrosomal protein 85provided by MGI
    Primary source
    MGI:MGI:1917262
    See related
    Ensembl:ENSMUSG00000037443
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ccdc21; AI173272; AI173504; 2410030J07Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 25.3), thymus adult (RPKM 18.0) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Cep85 in Genome Data Viewer
    Location:
    4; 4 D2.3
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (133857169..133914420, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (134129858..134187085, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (133685773..133743000, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene UBX domain protein 11 Neighboring gene SH3 domain binding glutamic acid-rich protein-like 3 Neighboring gene zona pellucida like domain containing 2 Neighboring gene cation channel, sperm associated 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within chromosome segregation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of protein kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of mitotic centrosome separation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in pericentriolar material ISO
    Inferred from Sequence Orthology
    more info
     
    located_in spindle pole ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    centrosomal protein of 85 kDa
    Names
    coiled-coil domain containing 21
    coiled-coil domain-containing protein 21

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_144527.3NP_653110.3  centrosomal protein of 85 kDa

      See identical proteins and their annotated locations for NP_653110.3

      Status: VALIDATED

      Source sequence(s)
      AK085545, AK141103, AV301648, AW123366, BY250554
      Consensus CDS
      CCDS18765.1
      UniProtKB/Swiss-Prot
      Q8BMK0
      Related
      ENSMUSP00000039889.6, ENSMUST00000040271.12
      Conserved Domains (1) summary
      COG1196
      Location:381652
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      133857169..133914420 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036164407.1XP_036020300.1  centrosomal protein of 85 kDa isoform X1

      Conserved Domains (1) summary
      COG1196
      Location:381652
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    2. XM_036164408.1XP_036020301.1  centrosomal protein of 85 kDa isoform X2

      Conserved Domains (1) summary
      COG1196
      Location:330601
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    3. XM_036164409.1XP_036020302.1  centrosomal protein of 85 kDa isoform X3

      Conserved Domains (1) summary
      COG1196
      Location:318589
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    Support Center