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    Cep85 centrosomal protein 85 [ Mus musculus (house mouse) ]

    Gene ID: 70012, updated on 31-Jan-2019

    Summary

    Official Symbol
    Cep85provided by MGI
    Official Full Name
    centrosomal protein 85provided by MGI
    Primary source
    MGI:MGI:1917262
    See related
    Ensembl:ENSMUSG00000037443
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ccdc21; AI173272; AI173504; 2410030J07Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 25.3), thymus adult (RPKM 18.0) and 28 other tissues See more
    Orthologs

    Genomic context

    See Cep85 in Genome Data Viewer
    Location:
    4; 4 D3
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (134129858..134187085, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (133685773..133743000, complement)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene UBX domain protein 11 Neighboring gene SH3 domain binding glutamic acid-rich protein-like 3 Neighboring gene predicted gene, 46894 Neighboring gene predicted gene 7534 Neighboring gene cation channel, sperm associated 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    chromosome segregation IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of protein kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of mitotic centrosome separation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule organizing center ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    pericentriolar material ISO
    Inferred from Sequence Orthology
    more info
     
    spindle pole ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    centrosomal protein of 85 kDa
    Names
    coiled-coil domain containing 21
    coiled-coil domain-containing protein 21

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_144527.3NP_653110.3  centrosomal protein of 85 kDa

      See identical proteins and their annotated locations for NP_653110.3

      Status: VALIDATED

      Source sequence(s)
      AK085545, AK141103, AV301648, AW123366, BY250554
      Consensus CDS
      CCDS18765.1
      UniProtKB/Swiss-Prot
      Q8BMK0
      Related
      ENSMUSP00000039889.5, ENSMUST00000040271.11
      Conserved Domains (3) summary
      pfam14662
      Location:454656
      KASH_CCD; Coiled-coil region of CCDC155 or KASH
      pfam16046
      Location:426605
      FAM76; FAM76 protein
      cl23720
      Location:553654
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      134129858..134187085 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011250331.2XP_011248633.1  centrosomal protein of 85 kDa isoform X2

      Conserved Domains (3) summary
      pfam14662
      Location:403605
      KASH_CCD; Coiled-coil region of CCDC155 or KASH
      pfam16046
      Location:375554
      FAM76; FAM76 protein
      cl23720
      Location:502603
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    2. XM_011250330.2XP_011248632.1  centrosomal protein of 85 kDa isoform X1

      See identical proteins and their annotated locations for XP_011248632.1

      UniProtKB/Swiss-Prot
      Q8BMK0
      Conserved Domains (3) summary
      pfam14662
      Location:454656
      KASH_CCD; Coiled-coil region of CCDC155 or KASH
      pfam16046
      Location:426605
      FAM76; FAM76 protein
      cl23720
      Location:553654
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    3. XM_006539164.1XP_006539227.1  centrosomal protein of 85 kDa isoform X3

      Conserved Domains (3) summary
      pfam14662
      Location:391593
      KASH_CCD; Coiled-coil region of CCDC155 or KASH
      pfam16046
      Location:363542
      FAM76; FAM76 protein
      cl23720
      Location:490591
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
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