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    Nabp2 nucleic acid binding protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 69917, updated on 23-Jun-2021

    Summary

    Official Symbol
    Nabp2provided by MGI
    Official Full Name
    nucleic acid binding protein 2provided by MGI
    Primary source
    MGI:MGI:1917167
    See related
    Ensembl:ENSMUSG00000025374
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Na; SS; SSB1; Obfc2; Obfc2b; 2610036N15Rik
    Expression
    Ubiquitous expression in CNS E14 (RPKM 13.1), whole brain E14.5 (RPKM 12.1) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Nabp2 in Genome Data Viewer
    Location:
    10; 10 D3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (128237263..128247426, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (128401394..128411548, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (127838451..127846852, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 52 Neighboring gene microRNA 6915 Neighboring gene solute carrier family 39 (metal ion transporter), member 5 Neighboring gene ring finger protein 41 Neighboring gene predicted gene, 26347 Neighboring gene nuclear encoded tRNA serine 2 (anticodon CGA)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Clone Names

    • MGC30353

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables DNA polymerase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables G-rich strand telomeric DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables single-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of SOSS complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of SOSS complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromosome, telomeric region IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in chromosome, telomeric region ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in site of double-strand break ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    SOSS complex subunit B1
    Names
    SOSS-B1
    oligonucleotide/oligosaccharide-binding fold containing 2B
    oligonucleotide/oligosaccharide-binding fold-containing protein 2B
    sensor of single-strand DNA complex subunit B1
    sensor of ssDNA subunit B1
    single-stranded DNA-binding protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001358972.1NP_001345901.1  SOSS complex subunit B1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC090489, BE988804, BX519720, CX238225
      Consensus CDS
      CCDS24276.1
      Conserved Domains (2) summary
      PRK14971
      Location:106179
      PRK14971; DNA polymerase III subunit gamma/tau
      cd04491
      Location:1895
      SoSSB_OBF; A subfamily of OB folds similar to the OB fold of the crenarchaeote Sulfolobus solfataricus single-stranded (ss) DNA-binding protein (SSoSSB). SSoSSB has a single OB fold, and it physically and functionally interacts with RNA polymerase. In vitro, SSoSSB ...
    2. NM_001358973.1NP_001345902.1  SOSS complex subunit B1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC090489, BE988804, BX519720, CX238225
      Conserved Domains (1) summary
      PRK14971
      Location:780
      PRK14971; DNA polymerase III subunit gamma/tau
    3. NM_027257.2NP_081533.1  SOSS complex subunit B1 isoform 1

      See identical proteins and their annotated locations for NP_081533.1

      Status: VALIDATED

      Source sequence(s)
      BE988804, BX519720, BY250791, CX238225
      Consensus CDS
      CCDS24276.1
      UniProtKB/Swiss-Prot
      Q8R2Y9
      Related
      ENSMUSP00000026439.8, ENSMUST00000026439.14
      Conserved Domains (2) summary
      PRK14971
      Location:106179
      PRK14971; DNA polymerase III subunit gamma/tau
      cd04491
      Location:1895
      SoSSB_OBF; A subfamily of OB folds similar to the OB fold of the crenarchaeote Sulfolobus solfataricus single-stranded (ss) DNA-binding protein (SSoSSB). SSoSSB has a single OB fold, and it physically and functionally interacts with RNA polymerase. In vitro, SSoSSB ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      128237263..128247426 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006514067.4XP_006514130.1  SOSS complex subunit B1 isoform X1

      See identical proteins and their annotated locations for XP_006514130.1

      UniProtKB/Swiss-Prot
      Q8R2Y9
      Conserved Domains (2) summary
      PRK14971
      Location:106179
      PRK14971; DNA polymerase III subunit gamma/tau
      cd04491
      Location:1895
      SoSSB_OBF; A subfamily of OB folds similar to the OB fold of the crenarchaeote Sulfolobus solfataricus single-stranded (ss) DNA-binding protein (SSoSSB). SSoSSB has a single OB fold, and it physically and functionally interacts with RNA polymerase. In vitro, SSoSSB ...
    2. XM_036155988.1XP_036011881.1  SOSS complex subunit B1 isoform X1

      Conserved Domains (2) summary
      PRK14971
      Location:106179
      PRK14971; DNA polymerase III subunit gamma/tau
      cd04491
      Location:1895
      SoSSB_OBF; A subfamily of OB folds similar to the OB fold of the crenarchaeote Sulfolobus solfataricus single-stranded (ss) DNA-binding protein (SSoSSB). SSoSSB has a single OB fold, and it physically and functionally interacts with RNA polymerase. In vitro, SSoSSB ...
    3. XM_006514066.4XP_006514129.1  SOSS complex subunit B1 isoform X1

      See identical proteins and their annotated locations for XP_006514129.1

      UniProtKB/Swiss-Prot
      Q8R2Y9
      Conserved Domains (2) summary
      PRK14971
      Location:106179
      PRK14971; DNA polymerase III subunit gamma/tau
      cd04491
      Location:1895
      SoSSB_OBF; A subfamily of OB folds similar to the OB fold of the crenarchaeote Sulfolobus solfataricus single-stranded (ss) DNA-binding protein (SSoSSB). SSoSSB has a single OB fold, and it physically and functionally interacts with RNA polymerase. In vitro, SSoSSB ...
    4. XM_030245253.2XP_030101113.1  SOSS complex subunit B1 isoform X1

      Related
      ENSMUSP00000128634.2, ENSMUST00000164199.8
      Conserved Domains (2) summary
      PRK14971
      Location:106179
      PRK14971; DNA polymerase III subunit gamma/tau
      cd04491
      Location:1895
      SoSSB_OBF; A subfamily of OB folds similar to the OB fold of the crenarchaeote Sulfolobus solfataricus single-stranded (ss) DNA-binding protein (SSoSSB). SSoSSB has a single OB fold, and it physically and functionally interacts with RNA polymerase. In vitro, SSoSSB ...
    5. XM_030245254.2XP_030101114.1  SOSS complex subunit B1 isoform X2

      Conserved Domains (1) summary
      PRK14971
      Location:780
      PRK14971; DNA polymerase III subunit gamma/tau
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