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    Eif1ad eukaryotic translation initiation factor 1A domain containing [ Mus musculus (house mouse) ]

    Gene ID: 69860, updated on 9-Dec-2024

    Summary

    Official Symbol
    Eif1adprovided by MGI
    Official Full Name
    eukaryotic translation initiation factor 1A domain containingprovided by MGI
    Primary source
    MGI:MGI:1917110
    See related
    Ensembl:ENSMUSG00000024841 AllianceGenome:MGI:1917110
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Eif1ad1; 2010003J03Rik
    Summary
    Predicted to enable RNA binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including adrenal gland; brain; genitourinary system; gut; and respiratory system. Orthologous to human EIF1AD (eukaryotic translation initiation factor 1A domain containing). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 20.2), thymus adult (RPKM 14.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Eif1ad in Genome Data Viewer
    Location:
    19 A; 19 4.31 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (5416841..5421546)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (5366813..5371518)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene cation channel, sperm associated 1 Neighboring gene cystatin E/M Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:5366783-5366974 Neighboring gene BAF nuclear assembly factor 1 Neighboring gene squamous cell carcinoma antigen recognized by T cells 1 Neighboring gene RIKEN cDNA D330050I16 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:5389816-5390049 Neighboring gene testis specific 10 interacting protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables translation initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in translational initiation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    probable RNA-binding protein EIF1AD
    Names
    eukaryotic translation initiation factor 1A domain-containing protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027236.2NP_081512.1  probable RNA-binding protein EIF1AD

      See identical proteins and their annotated locations for NP_081512.1

      Status: PROVISIONAL

      Source sequence(s)
      AC122861
      Consensus CDS
      CCDS29459.1
      UniProtKB/Swiss-Prot
      Q3THJ3, Q8K1C2, Q9D8F9
      Related
      ENSMUSP00000025759.8, ENSMUST00000025759.9
      Conserved Domains (1) summary
      cd05792
      Location:25102
      S1_eIF1AD_like; eukaryotic translation initiation factor 1A domain containing protein (eIF1AD)-like, S1-like RNA-binding domain. eIF1AD is also known as MGC11102 protein. Little is known about the function of eIF1AD. S1-like RNA-binding domains are found in a wide ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      5416841..5421546
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030251073.1XP_030106933.1  probable RNA-binding protein EIF1AD isoform X1

      UniProtKB/Swiss-Prot
      Q3THJ3, Q8K1C2, Q9D8F9
      Conserved Domains (1) summary
      cd05792
      Location:25102
      S1_eIF1AD_like; eukaryotic translation initiation factor 1A domain containing protein (eIF1AD)-like, S1-like RNA-binding domain. eIF1AD is also known as MGC11102 protein. Little is known about the function of eIF1AD. S1-like RNA-binding domains are found in a wide ...