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    Smap2 small ArfGAP 2 [ Mus musculus (house mouse) ]

    Gene ID: 69780, updated on 23-Jun-2021

    Summary

    Official Symbol
    Smap2provided by MGI
    Official Full Name
    small ArfGAP 2provided by MGI
    Primary source
    MGI:MGI:1917030
    See related
    Ensembl:ENSMUSG00000032870
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sm; Smap1l; AA408614; 1810031K02Rik
    Expression
    Ubiquitous expression in spleen adult (RPKM 26.9), frontal lobe adult (RPKM 20.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Smap2 in Genome Data Viewer
    Location:
    4; 4 D2.2
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (120825514..120874497, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (120968317..121017289, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (120640922..120689852, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene exonuclease 5 Neighboring gene zinc finger protein 69 Neighboring gene microRNA 7015 Neighboring gene collagen, type IX, alpha 2 Neighboring gene zinc metallopeptidase, STE24 Neighboring gene predicted gene, 23540

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    stromal membrane-associated protein 2
    Names
    stromal membrane-associated GTPase-activating protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133716.3NP_598477.2  stromal membrane-associated protein 2

      See identical proteins and their annotated locations for NP_598477.2

      Status: VALIDATED

      Source sequence(s)
      BC052413, BM944792, BQ175680
      Consensus CDS
      CCDS18598.1
      UniProtKB/Swiss-Prot
      Q7TN29
      Related
      ENSMUSP00000035800.8, ENSMUST00000043200.8
      Conserved Domains (2) summary
      pfam01412
      Location:13126
      ArfGap; Putative GTPase activating protein for Arf
      pfam09606
      Location:276416
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      120825514..120874497 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006503378.4XP_006503441.1  stromal membrane-associated protein 2 isoform X1

      Conserved Domains (2) summary
      pfam09606
      Location:196336
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cl28907
      Location:142
      ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
    2. XM_006503379.4XP_006503442.1  stromal membrane-associated protein 2 isoform X2

      Conserved Domains (1) summary
      pfam09606
      Location:195335
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    3. XM_006503380.3XP_006503443.1  stromal membrane-associated protein 2 isoform X3

      Conserved Domains (1) summary
      cd08859
      Location:16122
      ArfGap_SMAP2; Stromal membrane-associated protein 2; a subfamily of the ArfGAP family
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