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    Tfpt TCF3 (E2A) fusion partner [ Mus musculus (house mouse) ]

    Gene ID: 69714, updated on 23-Jun-2021

    Summary

    Official Symbol
    Tfptprovided by MGI
    Official Full Name
    TCF3 (E2A) fusion partnerprovided by MGI
    Primary source
    MGI:MGI:1916964
    See related
    Ensembl:ENSMUSG00000006335
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Am; FB1; Amida; AI450389; 2400004F01Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 12.3), CNS E14 (RPKM 9.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Tfpt in Genome Data Viewer
    Location:
    7; 7 A1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (3623323..3632928, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (3620324..3629929, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (3571926..3581486, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene osteoclast associated receptor Neighboring gene NADH:ubiquinone oxidoreductase subunit A3 Neighboring gene pre-mRNA processing factor 31 Neighboring gene predicted gene 15927 Neighboring gene CCR4-NOT transcription complex, subunit 3 Neighboring gene microRNA 3572

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA recombination IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in apoptotic signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in apoptotic signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within cellular response to DNA damage stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in positive regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of Ino80 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of Ino80 complex ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with actin filament ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    TCF3 fusion partner homolog
    Names
    protein amida

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001290381.1NP_001277310.1  TCF3 fusion partner homolog isoform 1

      See identical proteins and their annotated locations for NP_001277310.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AF267988, BY262757, CX768547
      Consensus CDS
      CCDS71873.1
      UniProtKB/Swiss-Prot
      Q3U1J1
      Related
      ENSMUSP00000104281.4, ENSMUST00000108641.10
    2. NM_023524.2NP_076013.1  TCF3 fusion partner homolog isoform 2

      See identical proteins and their annotated locations for NP_076013.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      AF267988, BY262757
      Consensus CDS
      CCDS20720.1
      UniProtKB/Swiss-Prot
      Q3U1J1
      Related
      ENSMUSP00000123636.2, ENSMUST00000155592.8

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      3623323..3632928 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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