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    Ccdc115 coiled-coil domain containing 115 [ Mus musculus (house mouse) ]

    Gene ID: 69668, updated on 9-May-2024


    Official Symbol
    Ccdc115provided by MGI
    Official Full Name
    coiled-coil domain containing 115provided by MGI
    Primary source
    See related
    Ensembl:ENSMUSG00000042111 AllianceGenome:MGI:1916918
    Gene type
    protein coding
    RefSeq status
    Mus musculus
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ccp1; 2310061I09Rik
    Predicted to enable unfolded protein binding activity. Predicted to be involved in cellular cation homeostasis; cellular response to increased oxygen levels; and lysosomal protein catabolic process. Located in lysosome. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spinal cord. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIo. Orthologous to human CCDC115 (coiled-coil domain containing 115). [provided by Alliance of Genome Resources, Apr 2022]
    Ubiquitous expression in CNS E11.5 (RPKM 16.7), placenta adult (RPKM 16.7) and 28 other tissues See more
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    Genomic context

    See Ccdc115 in Genome Data Viewer
    1 B; 1 13.22 cM
    Exon count:
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (34475751..34478753, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (34436670..34439672, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 37233 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:34491786-34491969 Neighboring gene microRNA 5103 Neighboring gene nuclear encoded tRNA glutamic acid 1 (anticodon TTC) Neighboring gene STARR-positive B cell enhancer ABC_E787 Neighboring gene IMP4, U3 small nucleolar ribonucleoprotein Neighboring gene predicted gene, 32504 Neighboring gene protein tyrosine phosphatase, non-receptor type 18

    Genomic regions, transcripts, and products


    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a



    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (1) 


    Products Interactant Other Gene Complex Source Pubs Description

    General gene information


    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables unfolded protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    Component Evidence Code Pubs
    located_in COPI-coated vesicle ISO
    Inferred from Sequence Orthology
    more info
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
    located_in endoplasmic reticulum-Golgi intermediate compartment ISO
    Inferred from Sequence Orthology
    more info
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    located_in lysosome IDA
    Inferred from Direct Assay
    more info
    part_of vacuolar proton-transporting V-type ATPase complex ISO
    Inferred from Sequence Orthology
    more info

    General protein information

    Preferred Names
    coiled-coil domain-containing protein 115
    coiled-coil protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027159.2NP_081435.1  coiled-coil domain-containing protein 115

      See identical proteins and their annotated locations for NP_081435.1

      Status: VALIDATED

      Source sequence(s)
      AC106841, AI853654, AK162237
      Consensus CDS
      Q3TS67, Q8VE99
      ENSMUSP00000042918.9, ENSMUST00000042493.10

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J


    1. NC_000067.7 Reference GRCm39 C57BL/6J

      34475751..34478753 complement
      GenBank, FASTA, Sequence Viewer (Graphics)