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    Ddx51 DEAD box helicase 51 [ Mus musculus (house mouse) ]

    Gene ID: 69663, updated on 27-Nov-2024

    Summary

    Official Symbol
    Ddx51provided by MGI
    Official Full Name
    DEAD box helicase 51provided by MGI
    Primary source
    MGI:MGI:1916913
    See related
    Ensembl:ENSMUSG00000029504 AllianceGenome:MGI:1916913
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2310061O04Rik
    Summary
    Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and RNA helicase activity. Predicted to be involved in rRNA processing. Predicted to be located in nucleolus. Predicted to be active in nucleus. Is expressed in embryo. Orthologous to human DDX51 (DEAD-box helicase 51). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in ovary adult (RPKM 7.5), CNS E11.5 (RPKM 7.0) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Ddx51 in Genome Data Viewer
    Location:
    5 F; 5 53.69 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (110801298..110810885)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (110653432..110663019)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene polypeptide N-acetylgalactosaminyltransferase 9 Neighboring gene STARR-seq mESC enhancer starr_13961 Neighboring gene NOC4 like Neighboring gene microRNA 7026 Neighboring gene E1A binding protein p400 Neighboring gene predicted gene, 22716

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP-dependent H2AZ histone chaperone activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP-dependent H3-H4 histone complex chaperone activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA clamp loader activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables chromatin extrusion motor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables cohesin loader activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in chromatin looping IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    ATP-dependent RNA helicase DDX51
    Names
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
    DEAD box protein 51
    NP_081432.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027156.3NP_081432.2  ATP-dependent RNA helicase DDX51

      See identical proteins and their annotated locations for NP_081432.2

      Status: VALIDATED

      Source sequence(s)
      BC060646, BY010157
      Consensus CDS
      CCDS19528.1
      UniProtKB/Swiss-Prot
      Q3U7M2, Q6P9R1
      Related
      ENSMUSP00000031478.6, ENSMUST00000031478.6
      Conserved Domains (3) summary
      PRK11192
      Location:176639
      PRK11192; ATP-dependent RNA helicase SrmB; Provisional
      pfam00271
      Location:462573
      Helicase_C; Helicase conserved C-terminal domain
      cl21455
      Location:176421
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      110801298..110810885
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_880400.3 RNA Sequence