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    Clybl citrate lyase beta like [ Mus musculus (house mouse) ]

    Gene ID: 69634, updated on 23-Jun-2021

    Summary

    Official Symbol
    Clyblprovided by MGI
    Official Full Name
    citrate lyase beta likeprovided by MGI
    Primary source
    MGI:MGI:1916884
    See related
    Ensembl:ENSMUSG00000025545
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cl; Clb; AI256068; 0610033J05Rik; 2310014M14Rik
    Expression
    Broad expression in kidney adult (RPKM 9.1), heart adult (RPKM 8.2) and 25 other tissues See more
    Orthologs
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    Genomic context

    See Clybl in Genome Data Viewer
    Location:
    14; 14 E5
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (122408289..122639646)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (122170994..122402234)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (122580916..122801456)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene transmembrane 9 superfamily member 2 Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene Neighboring gene RIKEN cDNA 1700108J01 gene Neighboring gene predicted gene 5089 Neighboring gene predicted gene, 25464 Neighboring gene predicted gene, 53847 Neighboring gene zinc finger protein of the cerebellum 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables (S)-citramalyl-CoA lyase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables (S)-citramalyl-CoA lyase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables (S)-citramalyl-CoA lyase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables magnesium ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables malate synthase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 

    General protein information

    Preferred Names
    citramalyl-CoA lyase, mitochondrial
    Names
    (3S)-malyl-CoA thioesterase
    beta-methylmalate synthase
    citrate lyase subunit beta-like protein, mitochondrial
    malate synthase
    NP_083832.2
    XP_030103854.1
    XP_030103856.1
    XP_030103857.1
    XP_036014733.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029556.3NP_083832.2  citramalyl-CoA lyase, mitochondrial precursor

      See identical proteins and their annotated locations for NP_083832.2

      Status: VALIDATED

      Source sequence(s)
      AC164315, AK009345, CX202248
      Consensus CDS
      CCDS27346.1
      UniProtKB/Swiss-Prot
      Q8R4N0
      Related
      ENSMUSP00000026625.6, ENSMUST00000026625.7
      Conserved Domains (1) summary
      COG2301
      Location:45335
      CitE; Citrate lyase beta subunit [Carbohydrate transport and metabolism]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      122408289..122639646
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036158840.1XP_036014733.1  citramalyl-CoA lyase, mitochondrial isoform X1

    2. XM_030247994.1XP_030103854.1  citramalyl-CoA lyase, mitochondrial isoform X2

      Conserved Domains (1) summary
      COG2301
      Location:1204
      CitE; Citrate lyase beta subunit [Carbohydrate transport and metabolism]
    3. XM_030247997.2XP_030103857.1  citramalyl-CoA lyase, mitochondrial isoform X3

      Conserved Domains (1) summary
      COG2301
      Location:1174
      CitE; Citrate lyase beta subunit [Carbohydrate transport and metabolism]
    4. XM_030247996.1XP_030103856.1  citramalyl-CoA lyase, mitochondrial isoform X3

      Conserved Domains (1) summary
      COG2301
      Location:1174
      CitE; Citrate lyase beta subunit [Carbohydrate transport and metabolism]
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