Format

Send to:

Choose Destination
    • Showing Current items.

    Fastkd3 FAST kinase domains 3 [ Mus musculus (house mouse) ]

    Gene ID: 69577, updated on 31-Jan-2019

    Summary

    Official Symbol
    Fastkd3provided by MGI
    Official Full Name
    FAST kinase domains 3provided by MGI
    Primary source
    MGI:MGI:1916827
    See related
    Ensembl:ENSMUSG00000021532
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AW048587; 2310010B21Rik
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 5.9), CNS E11.5 (RPKM 5.3) and 28 other tissues See more
    Orthologs

    Genomic context

    See Fastkd3 in Genome Data Viewer
    Location:
    13; 13 B3
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (68582100..68592338)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (68721125..68731156)

    Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene predicted gene 8016 Neighboring gene predicted gene, 46386 Neighboring gene RIKEN cDNA 1700001L19 gene Neighboring gene 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Neighboring gene predicted gene, 34903 Neighboring gene adenylate cyclase 2 Neighboring gene predicted gene, 34993

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cellular respiration ISO
    Inferred from Sequence Orthology
    more info
     
    cellular respiration ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    mitochondrial respiratory chain complex IV assembly ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of mitochondrial translation ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of mitochondrial mRNA stability ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    FAST kinase domain-containing protein 3, mitochondrial

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001330423.1NP_001317352.1  FAST kinase domain-containing protein 3, mitochondrial

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the functional protein. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK033189, CA560457, CJ265660, CT033781
      Consensus CDS
      CCDS36719.1
      UniProtKB/Swiss-Prot
      Q8BSN9
    2. NM_027123.5NP_081399.3  FAST kinase domain-containing protein 3, mitochondrial

      See identical proteins and their annotated locations for NP_081399.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK033189, CJ265660, CT033781
      Consensus CDS
      CCDS36719.1
      UniProtKB/Swiss-Prot
      Q8BSN9
      Related
      ENSMUSP00000061737.8, ENSMUST00000051784.9
      Conserved Domains (3) summary
      smart00952
      Location:594651
      RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
      pfam06743
      Location:410478
      FAST_1; FAST kinase-like protein, subdomain 1
      pfam08368
      Location:494580
      FAST_2; FAST kinase-like protein, subdomain 2

    RNA

    1. NR_138477.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) contains an alternate 5' exon and uses an alternate splice site in an internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AK032530, AK033189, CJ265660, CT033781
    2. NR_138478.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) contains an alternate 5' exon and uses alternate splice sites in the second exon, compared to variant 1. This variant is represented as non-coding because it lacks a large portion of the coding region found in variant 1.
      Source sequence(s)
      AK033189, AW988524, CJ265660, CT033781

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

      Range
      68582100..68592338
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006517364.3XP_006517427.1  FAST kinase domain-containing protein 3, mitochondrial isoform X1

      Conserved Domains (3) summary
      smart00952
      Location:631688
      RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
      pfam06743
      Location:447515
      FAST_1; FAST kinase-like protein, subdomain 1
      pfam08368
      Location:531617
      FAST_2; FAST kinase-like protein, subdomain 2
    2. XM_017315595.1XP_017171084.1  FAST kinase domain-containing protein 3, mitochondrial isoform X4

    3. XM_006517365.3XP_006517428.1  FAST kinase domain-containing protein 3, mitochondrial isoform X2

      Conserved Domains (3) summary
      smart00952
      Location:594651
      RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
      pfam06743
      Location:410478
      FAST_1; FAST kinase-like protein, subdomain 1
      pfam08368
      Location:494580
      FAST_2; FAST kinase-like protein, subdomain 2
    4. XM_006517366.3XP_006517429.1  FAST kinase domain-containing protein 3, mitochondrial isoform X3

      See identical proteins and their annotated locations for XP_006517429.1

      Conserved Domains (3) summary
      smart00952
      Location:397454
      RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
      pfam06743
      Location:213281
      FAST_1; FAST kinase-like protein, subdomain 1
      pfam08368
      Location:297383
      FAST_2; FAST kinase-like protein, subdomain 2
    5. XM_006517367.1XP_006517430.1  FAST kinase domain-containing protein 3, mitochondrial isoform X3

      See identical proteins and their annotated locations for XP_006517430.1

      Conserved Domains (3) summary
      smart00952
      Location:397454
      RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
      pfam06743
      Location:213281
      FAST_1; FAST kinase-like protein, subdomain 1
      pfam08368
      Location:297383
      FAST_2; FAST kinase-like protein, subdomain 2

    RNA

    1. XR_382449.3 RNA Sequence

    2. XR_382450.3 RNA Sequence

      Related
      ENSMUST00000223319.1
    Support Center