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    Klhdc2 kelch domain containing 2 [ Mus musculus (house mouse) ]

    Gene ID: 69554, updated on 5-Aug-2018

    Summary

    Official Symbol
    Klhdc2provided by MGI
    Official Full Name
    kelch domain containing 2provided by MGI
    Primary source
    MGI:MGI:1916804
    See related
    Ensembl:ENSMUSG00000020978 Vega:OTTMUSG00000023685
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    LCP; HCLP-1; D12Ertd522e; 2310022K15Rik
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 57.4), CNS E18 (RPKM 56.1) and 28 other tissues See more
    Orthologs

    Genomic context

    See Klhdc2 in Genome Data Viewer
    Location:
    12 C2; 12 28.77 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 12 NC_000078.6 (69296681..69310687)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (70397668..70411674)

    Chromosome 12 - NC_000078.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 9330151L19 gene Neighboring gene dynein, axonemal assembly factor 2 Neighboring gene polymerase (DNA directed), epsilon 2 (p59 subunit) Neighboring gene kelch domain containing 1 Neighboring gene nuclear export mediator factor Neighboring gene 7S RNA 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (3) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    kelch domain-containing protein 2
    Names
    endothelial differentiation inhibitory protein TNG

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027117.3NP_081393.2  kelch domain-containing protein 2

      See identical proteins and their annotated locations for NP_081393.2

      Status: VALIDATED

      Source sequence(s)
      AC099934, AK009481
      Consensus CDS
      CCDS25950.1
      UniProtKB/Swiss-Prot
      Q4G5Y1
      Related
      ENSMUSP00000021362.4, OTTMUSP00000028061, ENSMUST00000021362.4, OTTMUST00000058026
      Conserved Domains (3) summary
      sd00038
      Location:218265
      Kelch; KELCH repeat [structural motif]
      pfam13415
      Location:279326
      Kelch_3; Galactose oxidase, central domain
      cl26061
      Location:29296
      PLN02193; nitrile-specifier protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000078.6 Reference GRCm38.p4 C57BL/6J

      Range
      69296681..69310687
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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