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    H4c8 H4 clustered histone 8 [ Mus musculus (house mouse) ]

    Gene ID: 69386, updated on 23-Jun-2021

    Summary

    Official Symbol
    H4c8provided by MGI
    Official Full Name
    H4 clustered histone 8provided by MGI
    Primary source
    MGI:MGI:2448427
    See related
    Ensembl:ENSMUSG00000060981
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    H2c8; H4c1; H4c2; H4c3; H4c4; H4c6; H4c9; H4c11; H4c12; H4c14; H4f16; Hist1h; Hist1h4h; 1700024H08Rik
    Summary
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. [provided by RefSeq, Aug 2015]
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    Genomic context

    See H4c8 in Genome Data Viewer
    Location:
    13; 13 A3.1
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (23715214..23715648)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (23531044..23531478)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (23622919..23623388)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene nuclear encoded tRNA arginine 1 (anticodon TCG) Neighboring gene predicted gene 11335 Neighboring gene nuclear encoded tRNA methionine 9 (anticodon CAT) Neighboring gene H2A clustered histone 10 Neighboring gene H3 clustered histone 8

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    • Homologs of the H4c8 gene: The H4c8 gene is conserved in human, chimpanzee, Rhesus monkey, cow, rat, chicken, zebrafish, fruit fly, C.elegans, A.thaliana, rice, and frog.
    • Orthologs

    Clone Names

    • MGC41466

    General protein information

    Preferred Names
    histone H4
    Names
    H4 histone family, member A
    histone 1, H4h
    histone cluster 1, H4h

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153173.4NP_694813.1  histone H4

      See identical proteins and their annotated locations for NP_694813.1

      Status: REVIEWED

      Source sequence(s)
      AL592149
      Consensus CDS
      CCDS26340.1
      UniProtKB/Swiss-Prot
      P62806
      UniProtKB/TrEMBL
      B2RTM0
      Related
      ENSMUSP00000100037.4, ENSMUST00000102972.6
      Conserved Domains (1) summary
      PLN00035
      Location:1103
      PLN00035; histone H4; Provisional

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      23715214..23715648
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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