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    Asb9 ankyrin repeat and SOCS box-containing 9 [ Mus musculus (house mouse) ]

    Gene ID: 69299, updated on 26-Sep-2022

    Summary

    Official Symbol
    Asb9provided by MGI
    Official Full Name
    ankyrin repeat and SOCS box-containing 9provided by MGI
    Primary source
    MGI:MGI:1916549
    See related
    Ensembl:ENSMUSG00000031384 AllianceGenome:MGI:1916549
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700011M07Rik
    Summary
    Predicted to be involved in positive regulation of protein catabolic process and protein ubiquitination. Predicted to be located in mitochondrion. Is expressed in limb. Orthologous to human ASB9 (ankyrin repeat and SOCS box containing 9). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis adult (RPKM 58.3) See more
    Orthologs
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    Genomic context

    See Asb9 in Genome Data Viewer
    Location:
    X; X F5
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (163280899..163322748)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (164497903..164539752)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene ankyrin repeat and SOCS box-containing 11 Neighboring gene chromobox protein homolog 1-like Neighboring gene 40S ribosomal protein S28 pseudogene Neighboring gene motile sperm domain containing 2 Neighboring gene Fanconi anemia, complementation group B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within protein ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ankyrin repeat and SOCS box protein 9
    Names
    ASB-9
    ankyrin repeat and SOCS box-containing protein 9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027027.2NP_081303.1  ankyrin repeat and SOCS box protein 9

      See identical proteins and their annotated locations for NP_081303.1

      Status: VALIDATED

      Source sequence(s)
      AK005878
      Consensus CDS
      CCDS30524.1
      UniProtKB/Swiss-Prot
      Q91ZT8, Q9DAF7
      UniProtKB/TrEMBL
      A0A8C6HYW2
      Related
      ENSMUSP00000033756.3, ENSMUST00000033756.3
      Conserved Domains (5) summary
      cd00204
      Location:59183
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:69159
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:3385
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:3162
      ANK; ANK repeat [structural motif]
      cl02533
      Location:249290
      SOCS; SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/SOCS family proteins (in combination with a SH2 domain), ASBs (ankyrin repeat-containing proteins with a SOCS box), SSBs (SPRY domain-containing proteins ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      163280899..163322748
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)