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    Elf2 E74-like factor 2 [ Mus musculus (house mouse) ]

    Gene ID: 69257, updated on 23-Jun-2021

    Summary

    Official Symbol
    Elf2provided by MGI
    Official Full Name
    E74-like factor 2provided by MGI
    Primary source
    MGI:MGI:1916507
    See related
    Ensembl:ENSMUSG00000037174
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EU32; NERF; NERF-2; NERF-1A; NERF-1B; AW111824; BB183398; 2610036A20Rik; A230104O07Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 16.4), thymus adult (RPKM 9.2) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Elf2 in Genome Data Viewer
    Location:
    3; 3 C
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (51160141..51248101, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (51252720..51340683, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (51059587..51129909, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40044 Neighboring gene nocturnin Neighboring gene RIKEN cDNA 4930577N17 gene Neighboring gene nuclear encoded tRNA proline 7 (anticodon TGG) Neighboring gene nuclear encoded tRNA proline 5 (anticodon AGG)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC102660

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    ETS-related transcription factor Elf-2
    Names
    ets domain transcription factor
    ets family transcription factor ELF2A2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001291059.1NP_001277988.1  ETS-related transcription factor Elf-2 isoform 2

      See identical proteins and their annotated locations for NP_001277988.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
      Source sequence(s)
      AC118601, AC161183, AK146819
      Consensus CDS
      CCDS71242.1
      UniProtKB/Swiss-Prot
      Q9JHC9
      UniProtKB/TrEMBL
      Q3TVH6
      Related
      ENSMUSP00000061076.7, ENSMUST00000062009.14
      Conserved Domains (2) summary
      pfam00178
      Location:197277
      Ets; Ets-domain
      pfam12310
      Location:3108
      Elf-1_N; Transcription factor protein N terminal
    2. NM_001291062.1NP_001277991.1  ETS-related transcription factor Elf-2 isoform 3

      See identical proteins and their annotated locations for NP_001277991.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate 5' structure and an alternate splice site in the coding region compared to variant 1. The encoded isoform (3) is shorter and has a distinct N-terminus compared to isoform 1.
      Source sequence(s)
      AC118601, AC161183, AF256218
      Consensus CDS
      CCDS71240.1
      UniProtKB/Swiss-Prot
      Q9JHC9
      Related
      ENSMUSP00000103686.2, ENSMUST00000108051.8
      Conserved Domains (2) summary
      pfam00178
      Location:138217
      Ets; Ets-domain
      pfam12310
      Location:2048
      Elf-1_N; Transcription factor protein N terminal
    3. NM_001291063.1NP_001277992.1  ETS-related transcription factor Elf-2 isoform 4

      See identical proteins and their annotated locations for NP_001277992.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) uses an alternate 5' structure compared to variant 1. The encoded isoform (4) is shorter and has a distinct N-terminus compared to isoform 1.
      Source sequence(s)
      AC118601, AC161183, AF256219
      Consensus CDS
      CCDS71241.1
      UniProtKB/Swiss-Prot
      Q9JHC9
      Related
      ENSMUSP00000103688.3, ENSMUST00000108053.9
      Conserved Domains (2) summary
      pfam00178
      Location:150229
      Ets; Ets-domain
      pfam12310
      Location:2048
      Elf-1_N; Transcription factor protein N terminal
    4. NM_001356358.1NP_001343287.1  ETS-related transcription factor Elf-2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC118601, AC161183
      Conserved Domains (2) summary
      pfam00178
      Location:118198
      Ets; Ets-domain
      pfam12310
      Location:229
      Elf-1_N; Transcription factor protein N terminal
    5. NM_023502.2NP_075991.1  ETS-related transcription factor Elf-2 isoform 1

      See identical proteins and their annotated locations for NP_075991.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AC118601, AC161183, AF256217
      Consensus CDS
      CCDS17337.1
      UniProtKB/Swiss-Prot
      Q9JHC9
      Related
      ENSMUSP00000141197.2, ENSMUST00000194641.6
      Conserved Domains (2) summary
      pfam00178
      Location:209289
      Ets; Ets-domain
      pfam12310
      Location:3108
      Elf-1_N; Transcription factor protein N terminal

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      51160141..51248101 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017319714.3XP_017175203.1  ETS-related transcription factor Elf-2 isoform X5

      Conserved Domains (1) summary
      pfam00178
      Location:105185
      Ets; Ets-domain
    2. XM_036163288.1XP_036019181.1  ETS-related transcription factor Elf-2 isoform X2

      Conserved Domains (2) summary
      pfam00178
      Location:197277
      Ets; Ets-domain
      pfam12310
      Location:3108
      Elf-1_N; Transcription factor protein N terminal
    3. XM_030252804.1XP_030108664.1  ETS-related transcription factor Elf-2 isoform X6

      Conserved Domains (1) summary
      pfam00178
      Location:94173
      Ets; Ets-domain
    4. XM_036163287.1XP_036019180.1  ETS-related transcription factor Elf-2 isoform X1

      Related
      ENSMUSP00000126871.2, ENSMUST00000163748.8
      Conserved Domains (2) summary
      pfam00178
      Location:209289
      Ets; Ets-domain
      pfam12310
      Location:3108
      Elf-1_N; Transcription factor protein N terminal
    5. XM_030252807.1XP_030108667.1  ETS-related transcription factor Elf-2 isoform X7

      Conserved Domains (1) summary
      pfam00178
      Location:74154
      Ets; Ets-domain
    6. XM_006502031.4XP_006502094.1  ETS-related transcription factor Elf-2 isoform X3

      See identical proteins and their annotated locations for XP_006502094.1

      Conserved Domains (2) summary
      pfam00178
      Location:130210
      Ets; Ets-domain
      pfam12310
      Location:229
      Elf-1_N; Transcription factor protein N terminal
    7. XM_036163295.1XP_036019188.1  ETS-related transcription factor Elf-2 isoform X7

      Conserved Domains (1) summary
      pfam00178
      Location:74154
      Ets; Ets-domain
    8. XM_036163291.1XP_036019184.1  ETS-related transcription factor Elf-2 isoform X4

      Conserved Domains (2) summary
      pfam00178
      Location:118198
      Ets; Ets-domain
      pfam12310
      Location:229
      Elf-1_N; Transcription factor protein N terminal
    9. XM_036163289.1XP_036019182.1  ETS-related transcription factor Elf-2 isoform X3

      Conserved Domains (2) summary
      pfam00178
      Location:130210
      Ets; Ets-domain
      pfam12310
      Location:229
      Elf-1_N; Transcription factor protein N terminal
    10. XM_036163290.1XP_036019183.1  ETS-related transcription factor Elf-2 isoform X3

      Conserved Domains (2) summary
      pfam00178
      Location:130210
      Ets; Ets-domain
      pfam12310
      Location:229
      Elf-1_N; Transcription factor protein N terminal
    11. XM_036163292.1XP_036019185.1  ETS-related transcription factor Elf-2 isoform X5

      Conserved Domains (1) summary
      pfam00178
      Location:105185
      Ets; Ets-domain
    12. XM_030252805.1XP_030108665.1  ETS-related transcription factor Elf-2 isoform X6

      Conserved Domains (1) summary
      pfam00178
      Location:94173
      Ets; Ets-domain
    13. XM_036163293.1XP_036019186.1  ETS-related transcription factor Elf-2 isoform X5

      Conserved Domains (1) summary
      pfam00178
      Location:105185
      Ets; Ets-domain
    14. XM_030252806.1XP_030108666.1  ETS-related transcription factor Elf-2 isoform X7

      Conserved Domains (1) summary
      pfam00178
      Location:74154
      Ets; Ets-domain
    15. XM_006502034.5XP_006502097.1  ETS-related transcription factor Elf-2 isoform X7

      See identical proteins and their annotated locations for XP_006502097.1

      Conserved Domains (1) summary
      pfam00178
      Location:74154
      Ets; Ets-domain
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