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    Gtpbp4 GTP binding protein 4 [ Mus musculus (house mouse) ]

    Gene ID: 69237, updated on 23-Jun-2021

    Summary

    Official Symbol
    Gtpbp4provided by MGI
    Official Full Name
    GTP binding protein 4provided by MGI
    Primary source
    MGI:MGI:1916487
    See related
    Ensembl:ENSMUSG00000021149
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    No; Crf; NGB; Crfg; Nog1; Gtpbp3; 2610028C09Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 17.1), placenta adult (RPKM 10.1) and 23 other tissues See more
    Orthologs
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    Genomic context

    See Gtpbp4 in Genome Data Viewer
    Location:
    13; 13 A1
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (9022106..9046144, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (8972070..8996116, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (8971710..8995258, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 22115 Neighboring gene predicted gene, 23923 Neighboring gene isopentenyl-diphosphate delta isomerase 2 Neighboring gene predicted gene, 36264 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene La ribonucleoprotein domain family, member 4B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    GTP-binding protein 4; nucleolar GTP-binding protein 1
    Names
    GTP binding protein 3
    GTP-binding protein NGB
    Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB)
    chronic renal failure gene protein
    chronic renal failure protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027000.4NP_081276.2  GTP-binding protein 4

      See identical proteins and their annotated locations for NP_081276.2

      Status: PROVISIONAL

      Source sequence(s)
      AC124732, AC125484
      Consensus CDS
      CCDS26236.1
      UniProtKB/Swiss-Prot
      Q99ME9
      Related
      ENSMUSP00000152412.2, ENSMUST00000222098.2
      Conserved Domains (3) summary
      cd01897
      Location:169340
      NOG; Nucleolar GTP-binding protein (NOG)
      COG1084
      Location:5345
      Nog1; GTP-binding protein, GTP1/Obg family [General function prediction only]
      pfam08155
      Location:396446
      NOGCT; NOGCT (NUC087) domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      9022106..9046144 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017315592.3XP_017171081.1  nucleolar GTP-binding protein 1 isoform X1

      Conserved Domains (2) summary
      COG1084
      Location:5288
      Nog1; GTP-binding protein, GTP1/Obg family [General function prediction only]
      pfam08155
      Location:338389
      NOGCT; NOGCT (NUC087) domain
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