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    Dhx16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [ Mus musculus (house mouse) ]

    Gene ID: 69192, updated on 18-Apr-2019

    Summary

    Official Symbol
    Dhx16provided by MGI
    Official Full Name
    DEAH (Asp-Glu-Ala-His) box polypeptide 16provided by MGI
    Primary source
    MGI:MGI:1916442
    See related
    Ensembl:ENSMUSG00000024422
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    DBP2; Ddx16; mKIAA0577; 2410006N22Rik
    Expression
    Ubiquitous expression in thymus adult (RPKM 30.7), testis adult (RPKM 23.0) and 28 other tissues See more
    Orthologs

    Genomic context

    See Dhx16 in Genome Data Viewer
    Location:
    17; 17 B1
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (35879764..35892670)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (36016723..36029615)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene nurim (nuclear envelope membrane protein) Neighboring gene protein phosphatase 1, regulatory subunit 18 Neighboring gene RIKEN cDNA 2310061I04 gene Neighboring gene alpha tubulin acetyltransferase 1 Neighboring gene uncharacterized LOC102635200

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from BioSystems

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP-dependent 3'-5' RNA helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ATPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    U2-type precatalytic spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16
    Names
    DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 16
    NP_081263.2
    XP_006524936.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026987.2NP_081263.2  putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

      See identical proteins and their annotated locations for NP_081263.2

      Status: VALIDATED

      Source sequence(s)
      AI853344, AK010431, BC138205, BU054791, CJ141265
      Consensus CDS
      CCDS28710.1
      UniProtKB/TrEMBL
      G3X8X0, Q921Y1, Q9CRI3
      Related
      ENSMUSP00000025292.8, ENSMUST00000025292.14
      Conserved Domains (5) summary
      smart00487
      Location:402584
      DEXDc; DEAD-like helicases superfamily
      smart00847
      Location:801885
      HA2; Helicase associated domain (HA2) Add an annotation
      cd00046
      Location:419558
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd00079
      Location:583740
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
      pfam07717
      Location:9201018
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      35879764..35892670
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006524873.1XP_006524936.1  putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 isoform X1

      Conserved Domains (5) summary
      smart00487
      Location:402584
      DEXDc; DEAD-like helicases superfamily
      smart00847
      Location:806890
      HA2; Helicase associated domain (HA2) Add an annotation
      cd00046
      Location:419558
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd00079
      Location:583745
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
      pfam07717
      Location:9251023
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold

    RNA

    1. XR_876528.2 RNA Sequence

      Related
      ENSMUST00000174366.7
    2. XR_001782109.1 RNA Sequence

    Reference GRCm38.p4 NOD/MrkTac

    Genomic

    1. NT_187027.1 Reference GRCm38.p4 NOD/MrkTac

      Range
      2189291..2202140
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCm38.p4 NOD/ShiLtJ

    Genomic

    1. NT_187004.1 Reference GRCm38.p4 NOD/ShiLtJ

      Range
      2212913..2225762
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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