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    Snx4 sorting nexin 4 [ Mus musculus (house mouse) ]

    Gene ID: 69150, updated on 31-Jan-2019

    Summary

    Official Symbol
    Snx4provided by MGI
    Official Full Name
    sorting nexin 4provided by MGI
    Primary source
    MGI:MGI:1916400
    See related
    Ensembl:ENSMUSG00000022808
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI037066; 1810036H14Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 23.3), limb E14.5 (RPKM 14.6) and 28 other tissues See more
    Orthologs

    Genomic context

    See Snx4 in Genome Data Viewer
    Location:
    16; 16 B3
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 16 NC_000082.6 (33251456..33299562)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (33251542..33299648)

    Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 41447 Neighboring gene oxysterol binding protein-like 11 Neighboring gene RIKEN cDNA 1700007L15 gene Neighboring gene zinc finger protein 148

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from BioSystems

    • Endocytosis, organism-specific biosystem (from KEGG)
      Endocytosis, organism-specific biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
    • Endocytosis, conserved biosystem (from KEGG)
      Endocytosis, conserved biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    epidermal growth factor receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    insulin receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    leptin receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    lipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    phosphatidylinositol binding ISO
    Inferred from Sequence Orthology
    more info
     
    transferrin receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    endocytic recycling ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of histamine secretion by mast cell ISO
    Inferred from Sequence Orthology
    more info
     
    protein transport ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    SNARE complex ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasmic dynein complex ISO
    Inferred from Sequence Orthology
    more info
     
    early endosome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    endosome IEA
    Inferred from Electronic Annotation
    more info
     
    membrane ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_080557.2NP_542124.1  sorting nexin-4

      See identical proteins and their annotated locations for NP_542124.1

      Status: PROVISIONAL

      Source sequence(s)
      AC145198
      Consensus CDS
      CCDS28129.1
      UniProtKB/Swiss-Prot
      Q91YJ2
      Related
      ENSMUSP00000023502.4, ENSMUST00000023502.5
      Conserved Domains (3) summary
      cd06864
      Location:58184
      PX_SNX4; The phosphoinositide binding Phox Homology domain of Sorting Nexin 4
      cd07622
      Location:205448
      BAR_SNX4; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexin 4
      pfam11221
      Location:324398
      Med21; Subunit 21 of Mediator complex

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000082.6 Reference GRCm38.p4 C57BL/6J

      Range
      33251456..33299562
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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