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    Psmd11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 [ Mus musculus (house mouse) ]

    Gene ID: 69077, updated on 22-Aug-2021

    Summary

    Official Symbol
    Psmd11provided by MGI
    Official Full Name
    proteasome (prosome, macropain) 26S subunit, non-ATPase, 11provided by MGI
    Primary source
    MGI:MGI:1916327
    See related
    Ensembl:ENSMUSG00000017428
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    S; S9; P44.; P44.5; C78232; 1700089D09Rik; 1810019E17Rik; 2610024G20Rik; 2810055C24Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 25.8), liver E14 (RPKM 25.4) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Psmd11 in Genome Data Viewer
    Location:
    11; 11 B5
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (80319441..80364074)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (80428615..80473248)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (80242117..80285635)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 5730455P16 gene Neighboring gene zinc finger protein 207 Neighboring gene cyclin-dependent kinase 5, regulatory subunit 1 (p35) Neighboring gene predicted gene, 53690 Neighboring gene myosin ID

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables structural molecule activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in proteasome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in stem cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in ubiquitin-dependent protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of proteasome accessory complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of proteasome accessory complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of proteasome complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of proteasome regulatory particle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of proteasome regulatory particle, lid subcomplex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    26S proteasome non-ATPase regulatory subunit 11
    Names
    26S proteasome regulatory subunit RPN6
    26S proteasome regulatory subunit S9
    26S proteasome regulatory subunit p44.5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178616.3NP_848731.2  26S proteasome non-ATPase regulatory subunit 11

      See identical proteins and their annotated locations for NP_848731.2

      Status: VALIDATED

      Source sequence(s)
      AK136049, BC119138, BY092952
      Consensus CDS
      CCDS25133.1
      UniProtKB/Swiss-Prot
      Q8BG32
      UniProtKB/TrEMBL
      Q3UWW9, Q5BKQ9
      Related
      ENSMUSP00000017572.8, ENSMUST00000017572.14
      Conserved Domains (1) summary
      COG5159
      Location:17421
      RPN6; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      80319441..80364074
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011249223.4XP_011247525.1  26S proteasome non-ATPase regulatory subunit 11 isoform X1

      Conserved Domains (1) summary
      COG5159
      Location:28343
      RPN6; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]
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