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    Tmem258 transmembrane protein 258 [ Mus musculus (house mouse) ]

    Gene ID: 69038, updated on 31-Jan-2019

    Summary

    Official Symbol
    Tmem258provided by MGI
    Official Full Name
    transmembrane protein 258provided by MGI
    Primary source
    MGI:MGI:1916288
    See related
    Ensembl:ENSMUSG00000036372
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1810006K21Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 111.7), placenta adult (RPKM 60.9) and 28 other tissues See more
    Orthologs

    Genomic context

    See Tmem258 in Genome Data Viewer
    Location:
    19; 19 A
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 19 NC_000085.6 (10204202..10207824)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (10278692..10282314)

    Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene fatty acid desaturase 1 Neighboring gene microRNA 6993 Neighboring gene flap structure specific endonuclease 1 Neighboring gene myelin regulatory factor Neighboring gene diacylglycerol lipase, alpha Neighboring gene predicted gene, 30042

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    protein N-linked glycosylation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    oligosaccharyltransferase I complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    transmembrane protein 258
    Names
    UPF0197 transmembrane protein C11orf10 homolog
    dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258
    oligosaccharyl transferase subunit TMEM258

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163431.1NP_001156903.1  transmembrane protein 258 isoform 2

      See identical proteins and their annotated locations for NP_001156903.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) represents use of an alternate promoter and 5' UTR, and uses a downstream start codon, compared to variant 1. The resulting isoform (2) has a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AC132148, AV456553, BC058335
      Consensus CDS
      CCDS50386.1
      UniProtKB/TrEMBL
      E9Q853
      Related
      ENSMUSP00000128883.1, ENSMUST00000166412.1
      Conserved Domains (1) summary
      pfam05251
      Location:274
      UPF0197; Uncharacterized protein family (UPF0197)
    2. NM_026919.1NP_081195.1  transmembrane protein 258 isoform 1

      See identical proteins and their annotated locations for NP_081195.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK007351, AV456553, BB568308
      Consensus CDS
      CCDS50385.1
      UniProtKB/Swiss-Prot
      P61166
      UniProtKB/TrEMBL
      Q60FD1
      Related
      ENSMUSP00000044751.7, ENSMUST00000040372.13
      Conserved Domains (1) summary
      pfam05251
      Location:779
      UPF0197; Uncharacterized protein family (UPF0197)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000085.6 Reference GRCm38.p4 C57BL/6J

      Range
      10204202..10207824
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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