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    Ssu72 Ssu72 RNA polymerase II CTD phosphatase homolog (yeast) [ Mus musculus (house mouse) ]

    Gene ID: 68991, updated on 19-Sep-2021

    Summary

    Official Symbol
    Ssu72provided by MGI
    Official Full Name
    Ssu72 RNA polymerase II CTD phosphatase homolog (yeast)provided by MGI
    Primary source
    MGI:MGI:1916241
    See related
    Ensembl:ENSMUSG00000029038
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1190002E22Rik; 1500011L16Rik; 2610101M12Rik
    Expression
    Ubiquitous expression in adrenal adult (RPKM 59.1), colon adult (RPKM 50.6) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Ssu72 in Genome Data Viewer
    Location:
    4; 4 E2
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (155789272..155818336)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (155704815..155733879)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (155078924..155107988)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene matrix metallopeptidase 23 Neighboring gene mindbomb E3 ubiquitin protein ligase 2 Neighboring gene fibronectin type III domain containing 10 Neighboring gene predicted gene, 22573 Neighboring gene RIKEN cDNA 1500002C15 gene Neighboring gene transmembrane protein 240 Neighboring gene ATPase family, AAA domain containing 3A Neighboring gene ATPase family, AAA domain containing 3A, opposite strand

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA polymerase II CTD heptapeptide repeat phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables RNA polymerase II CTD heptapeptide repeat phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphoprotein phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in dephosphorylation of RNA polymerase II C-terminal domain IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in dephosphorylation of RNA polymerase II C-terminal domain ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mRNA polyadenylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in mRNA polyadenylation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in termination of RNA polymerase II transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    part_of mRNA cleavage and polyadenylation specificity factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    RNA polymerase II subunit A C-terminal domain phosphatase SSU72
    Names
    CTD phosphatase SSU72
    NP_081175.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026899.3NP_081175.2  RNA polymerase II subunit A C-terminal domain phosphatase SSU72

      See identical proteins and their annotated locations for NP_081175.2

      Status: VALIDATED

      Source sequence(s)
      AK019168, BB867926, BU842478, BY237911
      Consensus CDS
      CCDS19036.1
      UniProtKB/Swiss-Prot
      Q9CY97
      Related
      ENSMUSP00000030905.3, ENSMUST00000030905.9
      Conserved Domains (1) summary
      pfam04722
      Location:6194
      Ssu72; Ssu72-like protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      155789272..155818336
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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