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    Snrpa1 small nuclear ribonucleoprotein polypeptide A' [ Mus musculus (house mouse) ]

    Gene ID: 68981, updated on 23-Jun-2021

    Summary

    Official Symbol
    Snrpa1provided by MGI
    Official Full Name
    small nuclear ribonucleoprotein polypeptide A'provided by MGI
    Primary source
    MGI:MGI:1916231
    See related
    Ensembl:ENSMUSG00000030512
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1500015N06Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 37.4), liver E14 (RPKM 25.3) and 24 other tissues See more
    Orthologs
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    Genomic context

    See Snrpa1 in Genome Data Viewer
    Location:
    7; 7 C
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (65710084..65724335)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (66060336..66074587)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (73205222..73219473)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene 20684 Neighboring gene proprotein convertase subtilisin/kexin type 6 Neighboring gene predicted gene, 51486 Neighboring gene selenoprotein S Neighboring gene chondroitin sulfate synthase 1 Neighboring gene predicted gene, 23042

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC6298, MGC25531

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables U2 snRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in spermatogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of U2 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of U2 snRNP IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of U2-type catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U2-type precatalytic spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    U2 small nuclear ribonucleoprotein A'
    Names
    U2 snRNP A'

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021336.4NP_067311.4  U2 small nuclear ribonucleoprotein A'

      See identical proteins and their annotated locations for NP_067311.4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript.
      Source sequence(s)
      AC148973, AK153502
      Consensus CDS
      CCDS21342.1
      UniProtKB/Swiss-Prot
      P57784
      Related
      ENSMUSP00000117947.2, ENSMUST00000153609.8
      Conserved Domains (2) summary
      sd00031
      Location:2243
      LRR_1; leucine-rich repeat [structural motif]
      pfam14580
      Location:1175
      LRR_9; Leucine-rich repeat

    RNA

    1. NR_152094.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC148973, AK005256, D18388
      Related
      ENSMUST00000032723.9

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      65710084..65724335
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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