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    Dcaf12 DDB1 and CUL4 associated factor 12 [ Mus musculus (house mouse) ]

    Gene ID: 68970, updated on 27-Jul-2018

    Summary

    Official Symbol
    Dcaf12provided by MGI
    Official Full Name
    DDB1 and CUL4 associated factor 12provided by MGI
    Primary source
    MGI:MGI:1916220
    See related
    Ensembl:ENSMUSG00000028436 Vega:OTTMUSG00000006637
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Wdr40a; AA420338; AI851081; 1500001L20Rik; 5830424K06Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 28.9), liver E14 (RPKM 16.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Dcaf12 in Genome Data Viewer
    Location:
    4; 4 A5
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (41291300..41316731, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (41238333..41261934, complement)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene ubiquitin-associated protein 2 Neighboring gene predicted gene, 42273 Neighboring gene predicted gene, 46891 Neighboring gene ubiquitin-associated protein 1 Neighboring gene kinesin family member 24

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    Cul4-RING E3 ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Cul4-RING E3 ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    DDB1- and CUL4-associated factor 12
    Names
    WD repeat domain 40A
    WD repeat-containing protein 40A

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026893.3NP_081169.2  DDB1- and CUL4-associated factor 12

      See identical proteins and their annotated locations for NP_081169.2

      Status: VALIDATED

      Source sequence(s)
      AA207929, AK031089, AK173289, BY338453
      Consensus CDS
      CCDS18059.1
      UniProtKB/Swiss-Prot
      Q8BGZ3
      Related
      ENSMUSP00000030145.8, OTTMUSP00000007003, ENSMUST00000030145.8, OTTMUST00000015153
      Conserved Domains (3) summary
      COG2319
      Location:103378
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:144180
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:85279
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      41291300..41316731 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006538229.3XP_006538292.1  DDB1- and CUL4-associated factor 12 isoform X2

      Conserved Domains (3) summary
      COG2319
      Location:79354
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:120156
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:61255
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    2. XM_006538230.3XP_006538293.1  DDB1- and CUL4-associated factor 12 isoform X3

      See identical proteins and their annotated locations for XP_006538293.1

    3. XM_006538228.3XP_006538291.1  DDB1- and CUL4-associated factor 12 isoform X1

      Conserved Domains (3) summary
      COG2319
      Location:97372
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:138174
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:79273
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    4. XM_017320381.1XP_017175870.1  DDB1- and CUL4-associated factor 12 isoform X3

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