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    Foxk2 forkhead box K2 [ Mus musculus (house mouse) ]

    Gene ID: 68837, updated on 2-Oct-2018

    Summary

    Official Symbol
    Foxk2provided by MGI
    Official Full Name
    forkhead box K2provided by MGI
    Primary source
    MGI:MGI:1916087
    See related
    Ensembl:ENSMUSG00000039275 Vega:OTTMUSG00000004287
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ILF; Ilf1; 1110054H05Rik; 5730434B08Rik; 6230415M23Rik
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 17.4), ovary adult (RPKM 17.3) and 28 other tissues See more
    Orthologs

    Genomic context

    See Foxk2 in Genome Data Viewer
    Location:
    11; 11 E2
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (121259987..121309896)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (121121301..121171210)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing Neighboring gene cytochrome b 245 chaperone 1 Neighboring gene nuclear prelamin A recognition factor Neighboring gene WD repeat domain 45B Neighboring gene Rab40B, member RAS oncogene family Neighboring gene microRNA 7236

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    forkhead box protein K2
    Names
    cellular transcription factor ILF-1
    interleukin enhancer-binding factor 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080932.3NP_001074401.2  forkhead box protein K2 isoform 1

      See identical proteins and their annotated locations for NP_001074401.2

      Status: VALIDATED

      Source sequence(s)
      AL808021, EU882160
      Consensus CDS
      CCDS36393.2
      UniProtKB/Swiss-Prot
      Q3UCQ1
      Related
      ENSMUSP00000101719.1, OTTMUSP00000004677, ENSMUST00000106113.1
      Conserved Domains (2) summary
      cd00060
      Location:41145
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      pfam00250
      Location:249335
      Forkhead; Forkhead domain
    2. NM_001363033.1NP_001349962.1  forkhead box protein K2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AK150439, AL808021
      Conserved Domains (2) summary
      cd00060
      Location:41145
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      pfam00250
      Location:249334
      Forkhead; Forkhead domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      121259987..121309896
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011249218.1XP_011247520.1  forkhead box protein K2 isoform X1

      Conserved Domains (3) summary
      cd00060
      Location:41124
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      pfam00250
      Location:288374
      Forkhead; Forkhead domain
      cl00056
      Location:99154
      MH2; C-terminal Mad Homology 2 (MH2) domain
    2. XM_011249219.1XP_011247521.1  forkhead box protein K2 isoform X2

      Conserved Domains (3) summary
      cd00060
      Location:41124
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      pfam00250
      Location:288374
      Forkhead; Forkhead domain
      cl00056
      Location:99154
      MH2; C-terminal Mad Homology 2 (MH2) domain
    3. XM_011249220.1XP_011247522.1  forkhead box protein K2 isoform X3

      Conserved Domains (3) summary
      cd00060
      Location:41124
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      pfam00250
      Location:288374
      Forkhead; Forkhead domain
      cl00056
      Location:99154
      MH2; C-terminal Mad Homology 2 (MH2) domain
    4. XM_011249221.1XP_011247523.1  forkhead box protein K2 isoform X4

      Conserved Domains (3) summary
      cd00060
      Location:41124
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      pfam00250
      Location:288374
      Forkhead; Forkhead domain
      cl00056
      Location:99154
      MH2; C-terminal Mad Homology 2 (MH2) domain
    5. XM_006534082.1XP_006534145.1  forkhead box protein K2 isoform X5

      UniProtKB/Swiss-Prot
      Q3UCQ1
      Conserved Domains (2) summary
      cd00060
      Location:41145
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      pfam00250
      Location:249334
      Forkhead; Forkhead domain

    RNA

    1. XR_879734.1 RNA Sequence

    2. XR_879735.1 RNA Sequence

    3. XR_879736.2 RNA Sequence

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