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    Rgmb repulsive guidance molecule family member B [ Mus musculus (house mouse) ]

    Gene ID: 68799, updated on 26-Jun-2021

    Summary

    Official Symbol
    Rgmbprovided by MGI
    Official Full Name
    repulsive guidance molecule family member Bprovided by MGI
    Primary source
    MGI:MGI:1916049
    See related
    Ensembl:ENSMUSG00000048027
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    DR; DRAGON; 1110059F19Rik
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 29.6), colon adult (RPKM 24.5) and 23 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Rgmb in Genome Data Viewer
    Location:
    17; 17 A2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (16024923..16051508, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (15804661..15831246, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (15943217..15963550, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4933401D09 gene Neighboring gene RIKEN cDNA 5830433I10 gene Neighboring gene chromodomain helicase DNA binding protein 1 Neighboring gene predicted gene, 25598 Neighboring gene predicted gene 3292

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables coreceptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables identical protein binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in anchored component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in anchored component of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum-Golgi intermediate compartment IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    repulsive guidance molecule B
    Names
    DRG11-responsive axonal guidance and outgrowth of neurite
    RGM domain family, member B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001372256.1NP_001359185.1  repulsive guidance molecule B isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC102745
      Conserved Domains (2) summary
      pfam06534
      Location:270444
      RGM_C; Repulsive guidance molecule (RGM) C-terminus
      pfam06535
      Location:98265
      RGM_N; Repulsive guidance molecule (RGM) N-terminus
    2. NM_001372257.1NP_001359186.1  repulsive guidance molecule B isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC102745
      Conserved Domains (2) summary
      pfam06534
      Location:270444
      RGM_C; Repulsive guidance molecule (RGM) C-terminus
      pfam06535
      Location:98265
      RGM_N; Repulsive guidance molecule (RGM) N-terminus
    3. NM_001372258.1NP_001359187.1  repulsive guidance molecule B isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC102745
      Conserved Domains (2) summary
      pfam06534
      Location:270444
      RGM_C; Repulsive guidance molecule (RGM) C-terminus
      pfam06535
      Location:98265
      RGM_N; Repulsive guidance molecule (RGM) N-terminus
    4. NM_001372259.1NP_001359188.1  repulsive guidance molecule B isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC102745
      Consensus CDS
      CCDS37455.1
      Conserved Domains (2) summary
      pfam06534
      Location:229403
      RGM_C; Repulsive guidance molecule (RGM) C-terminus
      pfam06535
      Location:57224
      RGM_N; Repulsive guidance molecule (RGM) N-terminus
    5. NM_001372292.1NP_001359221.1  repulsive guidance molecule B isoform 3 precursor

      Status: VALIDATED

      Source sequence(s)
      AC102745
      Related
      ENSMUSP00000156285.2, ENSMUST00000232638.2
      Conserved Domains (1) summary
      pfam06535
      Location:57218
      RGM_N; Repulsive guidance molecule (RGM) N-terminus
    6. NM_178615.4NP_848730.2  repulsive guidance molecule B isoform 2 precursor

      See identical proteins and their annotated locations for NP_848730.2

      Status: VALIDATED

      Source sequence(s)
      AC102745
      Consensus CDS
      CCDS37455.1
      UniProtKB/Swiss-Prot
      Q7TQ33
      Related
      ENSMUSP00000126177.2, ENSMUST00000170578.3
      Conserved Domains (2) summary
      pfam06534
      Location:229403
      RGM_C; Repulsive guidance molecule (RGM) C-terminus
      pfam06535
      Location:57224
      RGM_N; Repulsive guidance molecule (RGM) N-terminus

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      16024923..16051508 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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