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    Taf11 TATA-box binding protein associated factor 11 [ Mus musculus (house mouse) ]

    Gene ID: 68776, updated on 23-Jun-2021

    Summary

    Official Symbol
    Taf11provided by MGI
    Official Full Name
    TATA-box binding protein associated factor 11provided by MGI
    Primary source
    MGI:MGI:1916026
    See related
    Ensembl:ENSMUSG00000024218
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PRO; TAF; 28kD; TAFI; TAF2I; PRO214; TAFII28; AI115401; AL024207; AW552398; 1110038O14Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 14.5), testis adult (RPKM 9.7) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Taf11 in Genome Data Viewer
    Location:
    17; 17 A3.3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (28120096..28128723, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (27901122..27909343, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (28038073..28044669, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene U1 small nuclear ribonucleoprotein C Neighboring gene UHRF1 (ICBP90) binding protein 1 Neighboring gene ankyrin repeat and SAM domain containing 1 Neighboring gene predicted gene, 35290 Neighboring gene tRNA splicing endonuclease 34 pseudogene Neighboring gene t-complex protein 11

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables TBP-class protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein N-terminus binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables thyroid hormone receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription factor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables vitamin D receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of transcription factor TFIID complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of transcription factor TFIID complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    transcription initiation factor TFIID subunit 11
    Names
    TAF(II)28
    TAFII-28
    TFIID subunit p30-beta
    transcription initiation factor TFIID 28 kDa subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001379368.1NP_001366297.1  transcription initiation factor TFIID subunit 11

      Status: VALIDATED

      Source sequence(s)
      AC126040
      Related
      ENSMUSP00000025057.5, ENSMUST00000025057.5
      Conserved Domains (1) summary
      pfam04719
      Location:108192
      TAFII28; hTAFII28-like protein conserved region
    2. NM_026836.3NP_081112.1  transcription initiation factor TFIID subunit 11

      See identical proteins and their annotated locations for NP_081112.1

      Status: VALIDATED

      Source sequence(s)
      AC126040, AK050689, AK133851, BQ030498
      Consensus CDS
      CCDS28571.1
      UniProtKB/Swiss-Prot
      Q99JX1
      Related
      ENSMUSP00000110498.2, ENSMUST00000114848.8
      Conserved Domains (1) summary
      pfam04719
      Location:108192
      TAFII28; hTAFII28-like protein conserved region

    RNA

    1. NR_166634.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC126040
    2. NR_166635.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC126040

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      28120096..28128723 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011246588.4XP_011244890.1  transcription initiation factor TFIID subunit 11 isoform X1

      See identical proteins and their annotated locations for XP_011244890.1

      UniProtKB/Swiss-Prot
      Q99JX1
      Conserved Domains (1) summary
      pfam04719
      Location:108192
      TAFII28; hTAFII28-like protein conserved region
    2. XM_006524862.5XP_006524925.1  transcription initiation factor TFIID subunit 11 isoform X1

      See identical proteins and their annotated locations for XP_006524925.1

      UniProtKB/Swiss-Prot
      Q99JX1
      Conserved Domains (1) summary
      pfam04719
      Location:108192
      TAFII28; hTAFII28-like protein conserved region
    3. XM_036160772.1XP_036016665.1  transcription initiation factor TFIID subunit 11 isoform X2

      Conserved Domains (1) summary
      cl02176
      Location:108136
      TAF11; TATA Binding Protein (TBP) Associated Factor 11 (TAF11) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex
    4. XM_036160771.1XP_036016664.1  transcription initiation factor TFIID subunit 11 isoform X2

      Conserved Domains (1) summary
      cl02176
      Location:108136
      TAF11; TATA Binding Protein (TBP) Associated Factor 11 (TAF11) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex
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