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    Rnf166 ring finger protein 166 [ Mus musculus (house mouse) ]

    Gene ID: 68718, updated on 23-Jun-2021

    Summary

    Official Symbol
    Rnf166provided by MGI
    Official Full Name
    ring finger protein 166provided by MGI
    Primary source
    MGI:MGI:1915968
    See related
    Ensembl:ENSMUSG00000014470
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Zfp31; Zfp313l; AW555115; 1110031E24Rik
    Expression
    Ubiquitous expression in thymus adult (RPKM 75.7), adrenal adult (RPKM 60.7) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Rnf166 in Genome Data Viewer
    Location:
    8; 8 E1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (123192884..123202813, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (122466145..122476074, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (124990047..124999964, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 9330133O14 gene Neighboring gene predicted gene, 20735 Neighboring gene snail family zinc finger 3 Neighboring gene cytosolic thiouridylase subunit 2 Neighboring gene piezo-type mechanosensitive ion channel component 1 Neighboring gene predicted gene, 26497

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within autophagy IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within immune system process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within innate immune response IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein polyubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    E3 ubiquitin-protein ligase RNF166
    Names
    RING-type E3 ubiquitin transferase RNF166
    zinc finger protein 313; zinc finger protein 228
    NP_001028314.1
    NP_001355299.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033142.3NP_001028314.1  E3 ubiquitin-protein ligase RNF166 isoform 1

      See identical proteins and their annotated locations for NP_001028314.1

      Status: VALIDATED

      Source sequence(s)
      AC114917
      Consensus CDS
      CCDS22740.1
      UniProtKB/Swiss-Prot
      Q3U9F6
      UniProtKB/TrEMBL
      A2RS02
      Related
      ENSMUSP00000014614.4, ENSMUST00000014614.4
      Conserved Domains (3) summary
      cd16549
      Location:3076
      RING-HC_RNF166; RING finger, HC subclass, found in RING finger protein 166 (RNF166) and similar proteins
      pfam05605
      Location:149208
      zf-Di19; Drought induced 19 protein (Di19), zinc-binding
      pfam18574
      Location:92124
      zf_C2HC_14; C2HC Zing finger domain
    2. NM_001368370.1NP_001355299.1  E3 ubiquitin-protein ligase RNF166 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC114917
      Conserved Domains (1) summary
      pfam05605
      Location:4099
      zf-Di19; Drought induced 19 protein (Di19), zinc-binding

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      123192884..123202813 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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