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    Slc44a2 solute carrier family 44, member 2 [ Mus musculus (house mouse) ]

    Gene ID: 68682, updated on 23-Jun-2021

    Summary

    Official Symbol
    Slc44a2provided by MGI
    Official Full Name
    solute carrier family 44, member 2provided by MGI
    Primary source
    MGI:MGI:1915932
    See related
    Ensembl:ENSMUSG00000057193
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CTL; CTL2; 1110028E10Rik
    Expression
    Broad expression in thymus adult (RPKM 112.2), lung adult (RPKM 80.3) and 23 other tissues See more
    Orthologs
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    Genomic context

    See Slc44a2 in Genome Data Viewer
    Location:
    9; 9 A3
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (21232015..21266324)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (21320719..21355028)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (21142296..21159472)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene cyclin dependent kinase inhibitor 2D Neighboring gene adaptor protein complex AP-1, mu 2 subunit Neighboring gene predicted gene, 39302 Neighboring gene predicted gene, 36198 Neighboring gene interleukin enhancer binding factor 3 Neighboring gene predicted gene, 16853

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2)  1 citation
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables choline transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables choline transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in choline transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in choline transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    choline transporter-like protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001199186.1NP_001186115.1  choline transporter-like protein 2 isoform 1

      See identical proteins and their annotated locations for NP_001186115.1

      Status: VALIDATED

      Source sequence(s)
      AK041533, BU756489, BY339157
      Consensus CDS
      CCDS90511.1
      UniProtKB/Swiss-Prot
      Q8BY89
      Related
      ENSMUSP00000150147.2, ENSMUST00000217461.2
      Conserved Domains (2) summary
      pfam04515
      Location:317673
      Choline_transpo; Plasma-membrane choline transporter
      cl01738
      Location:226322
      DUF898; Bacterial protein of unknown function (DUF898)
    2. NM_001359227.1NP_001346156.1  choline transporter-like protein 2 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC122525
      Conserved Domains (2) summary
      pfam04515
      Location:318673
      Choline_transpo; Plasma-membrane choline transporter
      cl26602
      Location:245275
      SunT; ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]
    3. NM_152808.3NP_690021.1  choline transporter-like protein 2 isoform 2

      See identical proteins and their annotated locations for NP_690021.1

      Status: VALIDATED

      Source sequence(s)
      AK048648, AK166695, BU756489
      Consensus CDS
      CCDS22903.1
      UniProtKB/Swiss-Prot
      Q8BY89
      Related
      ENSMUSP00000034697.8, ENSMUST00000034697.8
      Conserved Domains (2) summary
      pfam04515
      Location:319675
      Choline_transpo; Plasma-membrane choline transporter
      cl01738
      Location:228324
      DUF898; Bacterial protein of unknown function (DUF898)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      21232015..21266324
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011242593.3XP_011240895.1  choline transporter-like protein 2 isoform X1

      Conserved Domains (2) summary
      cl38913
      Location:258298
      ABC_6TM_exporters; Six-transmembrane helical domain of the ATP-binding cassette transporters
      pfam04515
      Location:341697
      Choline_transpo; Plasma-membrane choline transporter
    2. XM_030244550.1XP_030100410.1  choline transporter-like protein 2 isoform X2

      Conserved Domains (2) summary
      TIGR03375
      Location:268298
      type_I_sec_LssB; type I secretion system ATPase, LssB family
      pfam04515
      Location:341697
      Choline_transpo; Plasma-membrane choline transporter
    3. XM_036155232.1XP_036011125.1  choline transporter-like protein 2 isoform X1

      Conserved Domains (2) summary
      cl38913
      Location:258298
      ABC_6TM_exporters; Six-transmembrane helical domain of the ATP-binding cassette transporters
      pfam04515
      Location:341697
      Choline_transpo; Plasma-membrane choline transporter
    4. XM_006510576.3XP_006510639.1  choline transporter-like protein 2 isoform X3

      Conserved Domains (2) summary
      TIGR03375
      Location:247277
      type_I_sec_LssB; type I secretion system ATPase, LssB family
      pfam04515
      Location:320676
      Choline_transpo; Plasma-membrane choline transporter
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