Format

Send to:

Choose Destination
    • Showing Current items.

    Ube2c ubiquitin-conjugating enzyme E2C [ Mus musculus (house mouse) ]

    Gene ID: 68612, updated on 31-Aug-2021

    Summary

    Official Symbol
    Ube2cprovided by MGI
    Official Full Name
    ubiquitin-conjugating enzyme E2Cprovided by MGI
    Primary source
    MGI:MGI:1915862
    See related
    Ensembl:ENSMUSG00000001403
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D2Ertd695; D2Ertd695e; 1110015A16Rik
    Expression
    Broad expression in liver E14.5 (RPKM 259.5), liver E14 (RPKM 226.5) and 15 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Ube2c in Genome Data Viewer
    Location:
    2 H3; 2 85.27 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (164611849..164614822)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (164769929..164772902)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (164595429..164598402)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene WAP four-disulfide core domain 3 Neighboring gene deoxynucleotidyltransferase, terminal, interacting protein 1 Neighboring gene troponin C2, fast Neighboring gene sorting nexin family member 21 Neighboring gene acyl-CoA thioesterase 8

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin conjugating enzyme activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables ubiquitin conjugating enzyme activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables ubiquitin-like protein ligase binding ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to ubiquitin-protein transferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables ubiquitin-protein transferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in anaphase-promoting complex-dependent catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in anaphase-promoting complex-dependent catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in exit from mitosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in free ubiquitin chain polymerization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of exit from mitosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein K11-linked ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein K48-linked ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein polyubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in protein ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of mitotic metaphase/anaphase transition IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in ubiquitin-dependent protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of anaphase-promoting complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ubiquitin-conjugating enzyme E2 C
    Names
    (E3-independent) E2 ubiquitin-conjugating enzyme C
    E2 ubiquitin-conjugating enzyme C
    ubcH10
    ubiquitin carrier protein C
    ubiquitin-protein ligase C
    NP_081061.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026785.2NP_081061.1  ubiquitin-conjugating enzyme E2 C

      See identical proteins and their annotated locations for NP_081061.1

      Status: PROVISIONAL

      Source sequence(s)
      AK003722
      Consensus CDS
      CCDS17055.1
      UniProtKB/Swiss-Prot
      Q9D1C1
      UniProtKB/TrEMBL
      A2A4Z0
      Related
      ENSMUSP00000085581.7, ENSMUST00000088248.13
      Conserved Domains (1) summary
      pfam00179
      Location:34170
      UQ_con; Ubiquitin-conjugating enzyme

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      164611849..164614822
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center