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    Ube2c ubiquitin-conjugating enzyme E2C [ Mus musculus (house mouse) ]

    Gene ID: 68612, updated on 12-Aug-2018

    Summary

    Official Symbol
    Ube2cprovided by MGI
    Official Full Name
    ubiquitin-conjugating enzyme E2Cprovided by MGI
    Primary source
    MGI:MGI:1915862
    See related
    Ensembl:ENSMUSG00000001403 Vega:OTTMUSG00000001153
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D2Ertd695e; 1110015A16Rik
    Expression
    Broad expression in liver E14.5 (RPKM 259.5), liver E14 (RPKM 226.5) and 15 other tissues See more
    Orthologs

    Genomic context

    See Ube2c in Genome Data Viewer
    Location:
    2 H3; 2 85.27 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (164769929..164772902)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (164595429..164598402)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene WAP four-disulfide core domain 3 Neighboring gene deoxynucleotidyltransferase, terminal, interacting protein 1 Neighboring gene predicted gene 11457 Neighboring gene troponin C2, fast Neighboring gene sorting nexin family member 21 Neighboring gene acyl-CoA thioesterase 8

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    ubiquitin conjugating enzyme activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ubiquitin conjugating enzyme activity ISO
    Inferred from Sequence Orthology
    more info
     
    ubiquitin-like protein ligase binding ISO
    Inferred from Sequence Orthology
    more info
     
    ubiquitin-protein transferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to ubiquitin-protein transferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    anaphase-promoting complex-dependent catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    anaphase-promoting complex-dependent catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    exit from mitosis ISO
    Inferred from Sequence Orthology
    more info
     
    free ubiquitin chain polymerization ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of exit from mitosis ISO
    Inferred from Sequence Orthology
    more info
     
    protein K11-linked ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    protein K48-linked ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    protein ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    ubiquitin-dependent protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    anaphase-promoting complex ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ubiquitin-conjugating enzyme E2 C
    Names
    (E3-independent) E2 ubiquitin-conjugating enzyme C
    E2 ubiquitin-conjugating enzyme C
    ubcH10
    ubiquitin carrier protein C
    ubiquitin-protein ligase C
    NP_081061.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026785.2NP_081061.1  ubiquitin-conjugating enzyme E2 C

      See identical proteins and their annotated locations for NP_081061.1

      Status: PROVISIONAL

      Source sequence(s)
      AK003722
      Consensus CDS
      CCDS17055.1
      UniProtKB/Swiss-Prot
      Q9D1C1
      UniProtKB/TrEMBL
      A2A4Z0
      Related
      ENSMUSP00000085581.6, OTTMUSP00000001095, ENSMUST00000088248.12, OTTMUST00000002246
      Conserved Domains (1) summary
      pfam00179
      Location:34170
      UQ_con; Ubiquitin-conjugating enzyme

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      164769929..164772902
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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