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    Sgo2a shugoshin 2A [ Mus musculus (house mouse) ]

    Gene ID: 68549, updated on 5-Aug-2018

    Summary

    Official Symbol
    Sgo2aprovided by MGI
    Official Full Name
    shugoshin 2Aprovided by MGI
    Primary source
    MGI:MGI:1098767
    See related
    Ensembl:ENSMUSG00000026039 Vega:OTTMUSG00000021832
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sgol2; Sgol2a; Tripin; AU018846; AV008062; D1Ertd8e; 1110007N04Rik; 4932411A20Rik; 5730576N04Rik
    Expression
    Biased expression in CNS E11.5 (RPKM 7.1), placenta adult (RPKM 4.8) and 12 other tissues See more
    Orthologs

    Genomic context

    See Sgo2a in Genome Data Viewer
    Location:
    1 C1.3; 1 28.86 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (57985340..58026277)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (58042184..58083121)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene spermatogenesis associated, serine-rich 2-like Neighboring gene potassium channel tetramerisation domain containing 18 Neighboring gene aldehyde oxidase 1 Neighboring gene predicted gene, 39643 Neighboring gene aldehyde oxidase 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    chromosome segregation IEA
    Inferred from Electronic Annotation
    more info
     
    female meiotic nuclear division IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    male meiotic nuclear division IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    meiotic sister chromatid cohesion involved in meiosis I IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    meiotic sister chromatid cohesion, centromeric IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein localization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    chromosome, centromeric region IDA
    Inferred from Direct Assay
    more info
    PubMed 
    chromosome, centromeric region ISO
    Inferred from Sequence Orthology
    more info
     
    condensed chromosome, centromeric region IDA
    Inferred from Direct Assay
    more info
    PubMed 
    condensed nuclear chromosome, centromeric region IDA
    Inferred from Direct Assay
    more info
    PubMed 
    kinetochore IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitotic cohesin complex ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    shugoshin 2
    Names
    sgo2
    shugoshin-like 2
    shugoshin-like 2a

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001177867.1NP_001171338.1  shugoshin 2 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks a few of 5' exons but has an alternate 5' exon, as compared to variant 1. The resulting isoform (2) is shorter and has a different N-terminus, as compared to isoform 1.
      Source sequence(s)
      BC052742, CN716821
      UniProtKB/Swiss-Prot
      Q7TSY8
      Conserved Domains (1) summary
      pfam05539
      Location:35228
      Pneumo_att_G; Pneumovirinae attachment membrane glycoprotein G
    2. NM_199007.2NP_950172.1  shugoshin 2 isoform 1

      See identical proteins and their annotated locations for NP_950172.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AK042448, AK138621, BC052742
      Consensus CDS
      CCDS35574.1
      UniProtKB/Swiss-Prot
      Q7TSY8
      Related
      ENSMUSP00000027202.8, OTTMUSP00000024449, ENSMUST00000027202.8, OTTMUST00000051809
      Conserved Domains (1) summary
      pfam05539
      Location:135328
      Pneumo_att_G; Pneumovirinae attachment membrane glycoprotein G

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      57985340..58026277
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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