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    Sgo2a shugoshin 2A [ Mus musculus (house mouse) ]

    Gene ID: 68549, updated on 23-Jun-2021

    Summary

    Official Symbol
    Sgo2aprovided by MGI
    Official Full Name
    shugoshin 2Aprovided by MGI
    Primary source
    MGI:MGI:1098767
    See related
    Ensembl:ENSMUSG00000026039
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    T; Sg; Sgol2; Sgol2a; Tripin; D1Ertd8; AU018846; AV008062; D1Ertd8e; 1110007N04Rik; 4932411A20Rik; 5730576N04Rik
    Expression
    Biased expression in CNS E11.5 (RPKM 7.1), placenta adult (RPKM 4.8) and 12 other tissues See more
    Orthologs
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    Genomic context

    See Sgo2a in Genome Data Viewer
    Location:
    1 C1.3; 1 28.86 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (58024499..58065436)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (57985340..58026277)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (58042184..58083121)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene spermatogenesis associated, serine-rich 2-like Neighboring gene small nucleolar RNA U13 Neighboring gene potassium channel tetramerisation domain containing 18 Neighboring gene aldehyde oxidase 1 Neighboring gene predicted gene, 39643 Neighboring gene aldehyde oxidase 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within chromosome segregation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within female meiotic nuclear division IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in homologous chromosome segregation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within male meiotic nuclear division IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in meiotic sister chromatid cohesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within meiotic sister chromatid cohesion involved in meiosis I IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within meiotic sister chromatid cohesion, centromeric IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in mitotic sister chromatid segregation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within protein localization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome, centromeric region IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in chromosome, centromeric region ISO
    Inferred from Sequence Orthology
    more info
     
    located_in condensed chromosome, centromeric region IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in kinetochore IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in kinetochore IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of mitotic cohesin complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    shugoshin 2
    Names
    sgo2
    shugoshin-like 2
    shugoshin-like 2a

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001177867.1NP_001171338.1  shugoshin 2 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks a few of 5' exons but has an alternate 5' exon, as compared to variant 1. The resulting isoform (2) is shorter and has a different N-terminus, as compared to isoform 1.
      Source sequence(s)
      BC052742, CN716821
      UniProtKB/Swiss-Prot
      Q7TSY8
      Conserved Domains (1) summary
      pfam05539
      Location:35228
      Pneumo_att_G; Pneumovirinae attachment membrane glycoprotein G
    2. NM_199007.2NP_950172.1  shugoshin 2 isoform 1

      See identical proteins and their annotated locations for NP_950172.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AK042448, AK138621, BC052742
      Consensus CDS
      CCDS35574.1
      UniProtKB/Swiss-Prot
      Q7TSY8
      Related
      ENSMUSP00000027202.9, ENSMUST00000027202.9
      Conserved Domains (1) summary
      pfam05539
      Location:135328
      Pneumo_att_G; Pneumovirinae attachment membrane glycoprotein G

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      58024499..58065436
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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