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    Ndufaf4 NADH:ubiquinone oxidoreductase complex assembly factor 4 [ Mus musculus (house mouse) ]

    Gene ID: 68493, updated on 5-Mar-2024


    Official Symbol
    Ndufaf4provided by MGI
    Official Full Name
    NADH:ubiquinone oxidoreductase complex assembly factor 4provided by MGI
    Primary source
    See related
    Ensembl:ENSMUSG00000028261 AllianceGenome:MGI:1915743
    Gene type
    protein coding
    RefSeq status
    Mus musculus
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1110007M04Rik; 3000003G13Rik
    Predicted to enable calmodulin binding activity. Acts upstream of or within NADH dehydrogenase complex assembly. Located in mitochondrion. Is expressed in several structures, including alimentary system; liver lobe; lung; pectoral girdle and thoracic body wall musculature; and vibrissa. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 15. Orthologous to human NDUFAF4 (NADH:ubiquinone oxidoreductase complex assembly factor 4). [provided by Alliance of Genome Resources, Apr 2022]
    Ubiquitous expression in CNS E18 (RPKM 4.0), CNS E11.5 (RPKM 3.9) and 28 other tissues See more
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    Genomic context

    See Ndufaf4 in Genome Data Viewer
    4 A3; 4 10.52 cM
    Exon count:
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (24898083..24905001)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (24898083..24905001)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene kelch-like 32 Neighboring gene predicted gene, 31436 Neighboring gene STARR-seq mESC enhancer starr_09783 Neighboring gene predicted gene, 31379 Neighboring gene predicted gene, 46848 Neighboring gene RIKEN cDNA C230012O17 gene Neighboring gene G protein-coupled receptor 63 Neighboring gene four and a half LIM domains 5

    Genomic regions, transcripts, and products


    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem


    Products Interactant Other Gene Complex Source Pubs Description

    General gene information


    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    enables molecular_function ND
    No biological Data available
    more info
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    located_in mitochondrial membrane ISO
    Inferred from Sequence Orthology
    more info
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info

    General protein information

    Preferred Names
    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4
    NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4
    hormone-regulated proliferation-associated protein of 20 kDa homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026742.4NP_081018.1  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

      See identical proteins and their annotated locations for NP_081018.1

      Status: VALIDATED

      Source sequence(s)
      AK160341, AL772223, BY163651
      Consensus CDS
      Q3TV72, Q9D1H6
      ENSMUSP00000029925.4, ENSMUST00000029925.10
      Conserved Domains (1) summary
      UPF0240; uncharacterized protein family (UPF0240)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J


    1. NC_000070.7 Reference GRCm39 C57BL/6J

      GenBank, FASTA, Sequence Viewer (Graphics)