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    Mob1b MOB kinase activator 1B [ Mus musculus (house mouse) ]

    Gene ID: 68473, updated on 22-Aug-2021

    Summary

    Official Symbol
    Mob1bprovided by MGI
    Official Full Name
    MOB kinase activator 1Bprovided by MGI
    Primary source
    MGI:MGI:1915723
    See related
    Ensembl:ENSMUSG00000006262
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mobk; Mobkl1a; AU015450; B230364F10; 1110003E08Rik
    Expression
    Ubiquitous expression in bladder adult (RPKM 5.1), CNS E11.5 (RPKM 4.2) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Mob1b in Genome Data Viewer
    Location:
    5; 5 E1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (88868730..88906314)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (88720871..88758455)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (89149896..89187480)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 42107 Neighboring gene RUN and FYVE domain containing 3 Neighboring gene G-rich RNA sequence binding factor 1 Neighboring gene predicted gene 15682 Neighboring gene deoxycytidine kinase Neighboring gene solute carrier family 4 (anion exchanger), member 4 Neighboring gene makorin, ring finger protein 1, pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Clone Names

    • MGC129510, MGC129511

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables kinase activator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in hippo signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in hippo signaling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of protein phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of protein autophosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    MOB kinase activator 1B
    Names
    MOB1, Mps One Binder kinase activator-like 1A
    mob1 homolog 1A
    mps one binder kinase activator-like 1A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026735.2NP_081011.1  MOB kinase activator 1B

      See identical proteins and their annotated locations for NP_081011.1

      Status: VALIDATED

      Source sequence(s)
      AK042552, AK077320, AK162120
      Consensus CDS
      CCDS39139.1
      UniProtKB/Swiss-Prot
      Q8BPB0
      UniProtKB/TrEMBL
      Q3T9U1
      Related
      ENSMUSP00000006424.8, ENSMUST00000006424.8
      Conserved Domains (1) summary
      pfam03637
      Location:33204
      Mob1_phocein; Mob1/phocein family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      88868730..88906314
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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