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    Tbc1d10b TBC1 domain family, member 10b [ Mus musculus (house mouse) ]

    Gene ID: 68449, updated on 23-May-2018

    Summary

    Official Symbol
    Tbc1d10bprovided by MGI
    Official Full Name
    TBC1 domain family, member 10bprovided by MGI
    Primary source
    MGI:MGI:1915699
    See related
    Ensembl:ENSMUSG00000042492 Vega:OTTMUSG00000029407
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C87963; 1110003P22Rik
    Expression
    Ubiquitous expression in thymus adult (RPKM 22.9), ovary adult (RPKM 16.8) and 28 other tissues See more
    Orthologs

    Genomic context

    See Tbc1d10b in Genome Data Viewer
    Location:
    7; 7 F3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (127197459..127208468, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (134340973..134351982, complement)

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene TAR (HIV) RNA binding protein 2 pseudogene Neighboring gene CD2 antigen (cytoplasmic tail) binding protein 2 Neighboring gene myosin light chain, phosphorylatable, fast skeletal muscle Neighboring gene septin 1 Neighboring gene predicted gene 4532

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    GTPase activator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Rab GTPase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    activation of GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    retrograde transport, endosome to Golgi ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    TBC1 domain family member 10B
    Names
    protein wz3-85

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_144522.5NP_653105.3  TBC1 domain family member 10B

      See identical proteins and their annotated locations for NP_653105.3

      Status: VALIDATED

      Source sequence(s)
      AC122537, AK047320
      Consensus CDS
      CCDS40139.2
      UniProtKB/Swiss-Prot
      Q8BHL3
      Related
      ENSMUSP00000113307.1, OTTMUSP00000037617, ENSMUST00000120705.2, OTTMUST00000072879
      Conserved Domains (1) summary
      smart00164
      Location:343548
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

      Range
      127197459..127208468 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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