Format

Send to:

Choose Destination
    • Showing Current items.

    Tlcd1 TLC domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 68385, updated on 23-Jun-2021

    Summary

    Official Symbol
    Tlcd1provided by MGI
    Official Full Name
    TLC domain containing 1provided by MGI
    Primary source
    MGI:MGI:1915572
    See related
    Ensembl:ENSMUSG00000019437
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Expression
    Ubiquitous expression in adrenal adult (RPKM 31.4), mammary gland adult (RPKM 18.8) and 27 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Tlcd1 in Genome Data Viewer
    Location:
    11; 11 B5
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (78068956..78071646)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (78176716..78181019)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (77992268..77994274)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene TNF receptor associated factor 4 Neighboring gene NIMA (never in mitosis gene a)-related expressed kinase 8 Neighboring gene microRNA 7653 Neighboring gene small nucleolar RNA, C/D box 42A Neighboring gene ribosomal protein L23A Neighboring gene small nucleolar RNA, C/D box 4A

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • 0610007A15Rik, 0610030G03Rik

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in lipid homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in membrane assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in membrane assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in phospholipid homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in phospholipid homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in plasma membrane organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in plasma membrane organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of membrane lipid distribution IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of membrane lipid distribution ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    TLC domain-containing protein 1
    Names
    calfacilitin

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001291235.2NP_001278164.1  TLC domain-containing protein 1 isoform b

      See identical proteins and their annotated locations for NP_001278164.1

      Status: VALIDATED

      Source sequence(s)
      AK002265, AL591070, BG083251, BQ175335
      Conserved Domains (1) summary
      smart00724
      Location:7163
      TLC; TRAM, LAG1 and CLN8 homology domains
    2. NM_001291236.1NP_001278165.1  TLC domain-containing protein 1 isoform c

      See identical proteins and their annotated locations for NP_001278165.1

      Status: VALIDATED

      Source sequence(s)
      AK165432, AL591070, BQ175335
      Consensus CDS
      CCDS70257.1
      UniProtKB/Swiss-Prot
      Q99JT6
      Related
      ENSMUSP00000090556.8, ENSMUST00000092880.14
      Conserved Domains (1) summary
      smart00724
      Location:48217
      TLC; TRAM, LAG1 and CLN8 homology domains
    3. NM_001291237.2NP_001278166.1  TLC domain-containing protein 1 isoform c

      See identical proteins and their annotated locations for NP_001278166.1

      Status: VALIDATED

      Source sequence(s)
      AA671983, AK002265, AL591070, BQ175335
      Consensus CDS
      CCDS70257.1
      UniProtKB/Swiss-Prot
      Q99JT6
      Conserved Domains (1) summary
      smart00724
      Location:48217
      TLC; TRAM, LAG1 and CLN8 homology domains
    4. NM_026708.2NP_080984.1  TLC domain-containing protein 1 isoform a precursor

      See identical proteins and their annotated locations for NP_080984.1

      Status: VALIDATED

      Source sequence(s)
      AK161721, AK165432, AL591070, BQ175335
      Consensus CDS
      CCDS25092.1
      UniProtKB/Swiss-Prot
      Q99JT6
      Related
      ENSMUSP00000114202.2, ENSMUST00000127587.8
      Conserved Domains (1) summary
      smart00724
      Location:41234
      TLC; TRAM, LAG1 and CLN8 homology domains

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      78068956..78071646
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011249203.4XP_011247505.1  TLC domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011247505.1

      Conserved Domains (1) summary
      smart00724
      Location:7163
      TLC; TRAM, LAG1 and CLN8 homology domains
    Support Center