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    Ndufa8 NADH:ubiquinone oxidoreductase subunit A8 [ Mus musculus (house mouse) ]

    Gene ID: 68375, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ndufa8provided by MGI
    Official Full Name
    NADH:ubiquinone oxidoreductase subunit A8provided by MGI
    Primary source
    MGI:MGI:1915625
    See related
    Ensembl:ENSMUSG00000026895
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CI-19kD; CI-PGIV; AW261656; 0610033L03Rik
    Expression
    Ubiquitous expression in heart adult (RPKM 140.9), kidney adult (RPKM 86.4) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Ndufa8 in Genome Data Viewer
    Location:
    2; 2 B
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (35926336..35939350, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (36036324..36049338, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (35891854..35904812, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene tubulin tyrosine ligase-like family, member 11 Neighboring gene predicted gene, 35396 Neighboring gene predicted gene, 39798 Neighboring gene MORN repeat containing 5 Neighboring gene LIM homeobox protein 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, NADH to ubiquinone IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitochondrial respiratory chain complex I assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane HDA PubMed 
    located_in mitochondrial intermembrane space ISO
    Inferred from Sequence Orthology
    more info
     
    part_of mitochondrial respiratory chain complex I IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of mitochondrial respiratory chain complex I ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in respirasome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8
    Names
    NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8
    NADH-ubiquinone oxidoreductase 19 kDa subunit
    complex I-19kD
    complex I-PGIV
    NP_080979.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026703.3NP_080979.1  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8

      See identical proteins and their annotated locations for NP_080979.1

      Status: VALIDATED

      Source sequence(s)
      AL773525
      Consensus CDS
      CCDS15967.1
      UniProtKB/Swiss-Prot
      Q9DCJ5
      Related
      ENSMUSP00000065352.6, ENSMUST00000070112.6
      Conserved Domains (1) summary
      pfam06747
      Location:78111
      CHCH; CHCH domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      35926336..35939350 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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