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    Mto1 mitochondrial tRNA translation optimization 1 [ Mus musculus (house mouse) ]

    Gene ID: 68291, updated on 23-Jun-2021

    Summary

    Official Symbol
    Mto1provided by MGI
    Official Full Name
    mitochondrial tRNA translation optimization 1provided by MGI
    Primary source
    MGI:MGI:1915541
    See related
    Ensembl:ENSMUSG00000032342
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2310039H01Rik; 5730419A02Rik
    Expression
    Ubiquitous expression in adrenal adult (RPKM 18.7), ovary adult (RPKM 7.4) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Mto1 in Genome Data Viewer
    Location:
    9; 9 E1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (78355372..78381447)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (78443479..78474165)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (78296017..78321959)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene 8093 Neighboring gene cyclic GMP-AMP synthase Neighboring gene eukaryotic translation elongation factor 1 alpha 1 Neighboring gene predicted gene, 53210

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables flavin adenine dinucleotide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial tRNA wobble uridine modification IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within mitochondrial tRNA wobble uridine modification IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in tRNA methylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within tRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tRNA wobble uridine modification IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within tRNA wobble uridine modification IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    protein MTO1 homolog, mitochondrial
    Names
    mitochondrial translation optimization 1 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026658.2NP_080934.2  protein MTO1 homolog, mitochondrial precursor

      See identical proteins and their annotated locations for NP_080934.2

      Status: VALIDATED

      Source sequence(s)
      AF369902, BB811598, BY735135, CF173757
      Consensus CDS
      CCDS23363.1
      UniProtKB/Swiss-Prot
      Q923Z3
      UniProtKB/TrEMBL
      G5E889
      Related
      ENSMUSP00000034896.7, ENSMUST00000034896.13
      Conserved Domains (3) summary
      PRK05192
      Location:56669
      PRK05192; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated
      pfam13932
      Location:437653
      GIDA_assoc; GidA associated domain
      cl21454
      Location:357455
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      78355372..78381447
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_001779005.3 RNA Sequence

      Related
      ENSMUST00000148238.2
    2. XR_003947995.2 RNA Sequence

    3. XR_870765.4 RNA Sequence

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