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    Ciao2a cytosolic iron-sulfur assembly component 2A [ Mus musculus (house mouse) ]

    Gene ID: 68250, updated on 3-Feb-2019

    Summary

    Official Symbol
    Ciao2aprovided by MGI
    Official Full Name
    cytosolic iron-sulfur assembly component 2Aprovided by MGI
    Primary source
    MGI:MGI:1915500
    See related
    Ensembl:ENSMUSG00000032381
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fam96a; 5730536A07Rik
    Expression
    Ubiquitous expression in liver E14 (RPKM 28.8), liver E14.5 (RPKM 23.2) and 28 other tissues See more
    Orthologs

    Genomic context

    See Ciao2a in Genome Data Viewer
    Location:
    9; 9 C
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (66126611..66138968)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (65974418..65986775)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene peptidylprolyl isomerase B Neighboring gene sorting nexin 22 Neighboring gene sorting nexin 1 Neighboring gene death-associated protein kinase 2 Neighboring gene ribosomal protein S27 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    chromosome segregation IEA
    Inferred from Electronic Annotation
    more info
     
    iron-sulfur cluster assembly ISO
    Inferred from Sequence Orthology
    more info
     
    protein maturation by [4Fe-4S] cluster transfer IEA
    Inferred from Electronic Annotation
    more info
     
    protein maturation by iron-sulfur cluster transfer ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    CIA complex ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    cytosolic iron-sulfur assembly component 2A; MIP18 family protein FAM96A
    Names
    family with sequence similarity 96, member A

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001359210.1NP_001346139.1  cytosolic iron-sulfur assembly component 2A isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC112676, AC124439
      Conserved Domains (1) summary
      cl00941
      Location:3996
      DUF59; Domain of unknown function DUF59
    2. NM_026635.3NP_080911.1  cytosolic iron-sulfur assembly component 2A isoform 1 precursor

      See identical proteins and their annotated locations for NP_080911.1

      Status: VALIDATED

      Source sequence(s)
      AK077700, BE655498
      Consensus CDS
      CCDS23302.1
      UniProtKB/Swiss-Prot
      Q9DCL2
      Related
      ENSMUSP00000034945.5, ENSMUST00000034945.5
      Conserved Domains (1) summary
      cl00941
      Location:39156
      DUF59; Domain of unknown function DUF59

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      66126611..66138968
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011242805.1XP_011241107.1  MIP18 family protein FAM96A isoform X1

      Conserved Domains (1) summary
      cl00941
      Location:39124
      DUF59; Domain of unknown function DUF59
    2. XM_006511397.1XP_006511460.1  MIP18 family protein FAM96A isoform X2

      Conserved Domains (1) summary
      cl00941
      Location:3996
      DUF59; Domain of unknown function DUF59
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