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    Rpa3 replication protein A3 [ Mus musculus (house mouse) ]

    Gene ID: 68240, updated on 5-Aug-2018

    Summary

    Official Symbol
    Rpa3provided by MGI
    Official Full Name
    replication protein A3provided by MGI
    Primary source
    MGI:MGI:1915490
    See related
    Ensembl:ENSMUSG00000012483 Vega:OTTMUSG00000029297
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    14kDa; C330026P08Rik
    Expression
    Biased expression in CNS E11.5 (RPKM 31.8), liver E14 (RPKM 27.7) and 13 other tissues See more
    Orthologs

    Genomic context

    See Rpa3 in Genome Data Viewer
    Location:
    6; 6 A1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (8255936..8259141, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (8205936..8209141, complement)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene meiosis regulator for oocyte development Neighboring gene predicted gene, 46951 Neighboring gene UMAP1-MVP12 associated (UMA) domain containing 1 Neighboring gene predicted gene, 46952 Neighboring gene lysyl-tRNA synthetase pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    damaged DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    damaged DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    single-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    single-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    DNA recombination IEA
    Inferred from Electronic Annotation
    more info
     
    DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    DNA replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    DNA replication ISO
    Inferred from Sequence Orthology
    more info
     
    base-excision repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    base-excision repair ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to DNA damage stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    double-strand break repair via homologous recombination IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    double-strand break repair via homologous recombination ISO
    Inferred from Sequence Orthology
    more info
     
    mismatch repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mismatch repair ISO
    Inferred from Sequence Orthology
    more info
     
    nucleotide-excision repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleotide-excision repair ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of mitotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    DNA replication factor A complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    DNA replication factor A complex ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    site of double-strand break IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    replication protein A 14 kDa subunit
    Names
    RF-A protein 3
    RP-A p14
    replication factor A protein 3

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026632.4NP_080908.1  replication protein A 14 kDa subunit

      See identical proteins and their annotated locations for NP_080908.1

      Status: VALIDATED

      Source sequence(s)
      AK009916, BU757427, BY057686
      Consensus CDS
      CCDS19909.1
      UniProtKB/Swiss-Prot
      Q9CQ71
      Related
      ENSMUSP00000012627.4, OTTMUSP00000037414, ENSMUST00000012627.4, OTTMUST00000072597
      Conserved Domains (1) summary
      pfam08661
      Location:5113
      Rep_fac-A_3; Replication factor A protein 3

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

      Range
      8255936..8259141 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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