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    Spindoc spindlin interactor and repressor of chromatin binding [ Mus musculus (house mouse) ]

    Gene ID: 68229, updated on 31-Jan-2019

    Summary

    Official Symbol
    Spindocprovided by MGI
    Official Full Name
    spindlin interactor and repressor of chromatin bindingprovided by MGI
    Primary source
    MGI:MGI:2147611
    See related
    Ensembl:ENSMUSG00000024970
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI846148; SPIN-DOC; 1700105P06Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 16.5), thymus adult (RPKM 10.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Spindoc in Genome Data Viewer
    Location:
    19; 19 A
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 19 NC_000085.6 (7356463..7383051, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (7430954..7457516, complement)

    Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene REST corepressor 2 Neighboring gene MAP/microtubule affinity regulating kinase 2 Neighboring gene uncharacterized LOC102639888 Neighboring gene predicted gene, 46647 Neighboring gene RIKEN cDNA 1700105P06 gene Neighboring gene RAB11B, member RAS oncogene family, pseudogene 2 Neighboring gene predicted gene, 18842

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    negative regulation of transcription, DNA-templated IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    spindlin interactor and repressor of chromatin-binding protein; uncharacterized protein C11orf84 homolog
    Names
    SPIN1-docking protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033139.3NP_001028311.2  spindlin interactor and repressor of chromatin-binding protein isoform 1

      See identical proteins and their annotated locations for NP_001028311.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC129188, AK142757, AK163590, CJ166493
      Consensus CDS
      CCDS29523.1
      UniProtKB/Swiss-Prot
      Q05AH6
      Related
      ENSMUSP00000025924.2, ENSMUST00000025924.2
    2. NM_001167831.1NP_001161303.1  spindlin interactor and repressor of chromatin-binding protein isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AC129188, AK163590, CJ166493
      UniProtKB/Swiss-Prot
      Q05AH6

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000085.6 Reference GRCm38.p4 C57BL/6J

      Range
      7356463..7383051 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011247332.2XP_011245634.1  uncharacterized protein C11orf84 homolog isoform X2

    2. XM_011247331.2XP_011245633.1  uncharacterized protein C11orf84 homolog isoform X1

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