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    Eif3h eukaryotic translation initiation factor 3, subunit H [ Mus musculus (house mouse) ]

    Gene ID: 68135, updated on 23-Jun-2021

    Summary

    Official Symbol
    Eif3hprovided by MGI
    Official Full Name
    eukaryotic translation initiation factor 3, subunit Hprovided by MGI
    Primary source
    MGI:MGI:1915385
    See related
    Ensembl:ENSMUSG00000022312
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    40kD; Eif3; EIF3-P; Eif3s3; EIF3-ga; EIF3-P40; EIF3-gamma; 1110008A16Rik; 9430017H16Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 124.1), CNS E14 (RPKM 118.9) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Eif3h in Genome Data Viewer
    Location:
    15; 15 C
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (51649956..51729033, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (51786563..51865461, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (51618109..51697007, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 34503 Neighboring gene predicted gene, 41320 Neighboring gene predicted gene, 34678 Neighboring gene UTP23 small subunit processome component Neighboring gene predicted gene, 48923

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    • Chemically induced (ENU) (2)  1 citation

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC107627

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables deubiquitinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables isopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metallopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    contributes_to translation initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    contributes_to translation initiation factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    contributes_to translation initiation factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of eukaryotic 43S preinitiation complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of eukaryotic translation initiation factor 3 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of eukaryotic translation initiation factor 3 complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of eukaryotic translation initiation factor 3 complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of eukaryotic translation initiation factor 3 complex, eIF3m IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in polysomal ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    eukaryotic translation initiation factor 3 subunit H
    Names
    eIF-3-gamma
    eIF3 p40 subunit
    eIF3h
    eukaryotic translation initiation factor 3 subunit 3
    eukaryotic translation initiation factor 3, subunit 3 (gamma)
    eukaryotic translation initiation factor 3, subunit 3 (gamma, 40kD)

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_080635.1NP_542366.1  eukaryotic translation initiation factor 3 subunit H

      See identical proteins and their annotated locations for NP_542366.1

      Status: PROVISIONAL

      Source sequence(s)
      BC014755
      Consensus CDS
      CCDS27461.1
      UniProtKB/Swiss-Prot
      Q91WK2
      UniProtKB/TrEMBL
      Q5M9L0
      Related
      ENSMUSP00000022925.9, ENSMUST00000022925.10
      Conserved Domains (1) summary
      cd08065
      Location:37300
      MPN_eIF3h; Mpr1p, Pad1p N-terminal (MPN) domains without catalytic isopeptidase activity, found in eIF2h

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      51649956..51729033 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036159559.1XP_036015452.1  eukaryotic translation initiation factor 3 subunit H isoform X1

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