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    Entr1 endosome associated trafficking regulator 1 [ Mus musculus (house mouse) ]

    Gene ID: 68112, updated on 23-Jun-2021

    Summary

    Official Symbol
    Entr1provided by MGI
    Official Full Name
    endosome associated trafficking regulator 1provided by MGI
    Primary source
    MGI:MGI:1915362
    See related
    Ensembl:ENSMUSG00000026927
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sdcca; Sdccag3; C330016H24Rik; C630038K21Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 146.9), CNS E18 (RPKM 52.5) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Entr1 in Genome Data Viewer
    Location:
    2; 2 A3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (26272810..26279352, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (26382798..26389340, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (26238320..26244836, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene 13562 Neighboring gene caspase recruitment domain family, member 9 Neighboring gene small nuclear RNA activating complex, polypeptide 4 Neighboring gene peptidase (mitochondrial processing) alpha Neighboring gene inositol polyphosphate-5-phosphatase E Neighboring gene SEC16 homolog A, endoplasmic reticulum export factor Neighboring gene RIKEN cDNA 0610009E02 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell projection organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in endocytic recycling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in positive regulation of cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of protein localization to cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in positive regulation of protein localization to cilium ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of cytokinesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in early endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in early endosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in midbody IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in midbody ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in recycling endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in recycling endosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of retromer complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    endosome-associated-trafficking regulator 1
    Names
    serologically defined colon cancer antigen 3 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001085407.1NP_001078876.1  endosome-associated-trafficking regulator 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AK082787, AK163690, BY104480
      Consensus CDS
      CCDS50541.1
      UniProtKB/Swiss-Prot
      A2AIW0
      Related
      ENSMUSP00000028293.6, ENSMUST00000028293.12
      Conserved Domains (1) summary
      pfam16034
      Location:147317
      JAKMIP_CC3; JAKMIP CC3 domain
    2. NM_001085408.1NP_001078877.1  endosome-associated-trafficking regulator 1 isoform 4

      See identical proteins and their annotated locations for NP_001078877.1

      Status: VALIDATED

      Source sequence(s)
      AK163690, AW743523, BY104480
      Consensus CDS
      CCDS50540.1
      UniProtKB/Swiss-Prot
      A2AIW0
      Related
      ENSMUSP00000077133.7, ENSMUST00000077983.13
      Conserved Domains (1) summary
      pfam16034
      Location:124294
      JAKMIP_CC3; JAKMIP CC3 domain
    3. NM_026563.3NP_080839.2  endosome-associated-trafficking regulator 1 isoform 1

      See identical proteins and their annotated locations for NP_080839.2

      Status: VALIDATED

      Source sequence(s)
      AK014885, AK163690, BY104480
      Consensus CDS
      CCDS15803.2
      UniProtKB/Swiss-Prot
      A2AIW0
      Related
      ENSMUSP00000109737.4, ENSMUST00000114102.10
      Conserved Domains (1) summary
      pfam16034
      Location:197367
      JAKMIP_CC3; JAKMIP CC3 domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      26272810..26279352 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030252001.1XP_030107861.1  endosome-associated-trafficking regulator 1 isoform X3

      Conserved Domains (1) summary
      TIGR02169
      Location:186285
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    2. XM_006498261.2XP_006498324.1  endosome-associated-trafficking regulator 1 isoform X1

      Conserved Domains (1) summary
      pfam15898
      Location:269357
      PRKG1_interact; cGMP-dependent protein kinase interacting domain
    3. XM_030252003.1XP_030107863.1  endosome-associated-trafficking regulator 1 isoform X5

      Conserved Domains (1) summary
      TIGR02169
      Location:106205
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    4. XM_006498262.5XP_006498325.1  endosome-associated-trafficking regulator 1 isoform X2

      UniProtKB/TrEMBL
      A2AIW3
      Related
      ENSMUSP00000109735.4, ENSMUST00000114100.10
      Conserved Domains (1) summary
      TIGR02168
      Location:228350
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    5. XM_030252002.2XP_030107862.1  endosome-associated-trafficking regulator 1 isoform X4

      Conserved Domains (1) summary
      TIGR02168
      Location:98220
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    6. XM_036162513.1XP_036018406.1  endosome-associated-trafficking regulator 1 isoform X4

      Conserved Domains (1) summary
      TIGR02168
      Location:98220
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    RNA

    1. XR_003953706.1 RNA Sequence

    2. XR_003953705.2 RNA Sequence

    3. XR_003953703.2 RNA Sequence

    4. XR_003953704.2 RNA Sequence

    5. XR_004940714.1 RNA Sequence

    6. XR_374113.2 RNA Sequence

    7. XR_374114.2 RNA Sequence

    8. XR_003953702.1 RNA Sequence

    9. XR_004940713.1 RNA Sequence

    10. XR_004940712.1 RNA Sequence

    11. XR_003953701.1 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_030155.2: Suppressed sequence

      Description
      NM_030155.2: This RefSeq was temporarily suppressed because currently there is not sufficient data to support this transcript, and it contains a deletion compared to available sequence data that results in a frameshift.
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