Format

Send to:

Choose Destination
    • Showing Current items.

    Dynll2 dynein light chain LC8-type 2 [ Mus musculus (house mouse) ]

    Gene ID: 68097, updated on 5-Sep-2021

    Summary

    Official Symbol
    Dynll2provided by MGI
    Official Full Name
    dynein light chain LC8-type 2provided by MGI
    Primary source
    MGI:MGI:1915347
    See related
    Ensembl:ENSMUSG00000020483
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    DLC8; Dlc2; DLC8b; C87222; 1700064A15Rik; 6720463E02Rik
    Expression
    Ubiquitous expression in cerebellum adult (RPKM 107.7), testis adult (RPKM 91.9) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Dynll2 in Genome Data Viewer
    Location:
    11; 11 C
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (87870351..87892746, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (87979525..88003817, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (87793027..87811800, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene ubiquitin-conjugating enzyme MHR6BN pseudogene Neighboring gene olfactory receptor enhancer Sifnos Neighboring gene predicted gene, 38610 Neighboring gene serine and arginine-rich splicing factor 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables dynein intermediate chain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables dynein light intermediate chain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables scaffold protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in microtubule-based process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in 9+0 non-motile cilium ISO
    Inferred from Sequence Orthology
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    part_of cytoplasmic dynein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of cytoplasmic dynein complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    part_of cytoplasmic dynein complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    part_of dynein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    part_of microtubule associated complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of myosin V complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in postsynapse ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    dynein light chain 2, cytoplasmic
    Names
    8 kDa dynein light chain b

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001168471.1NP_001161943.1  dynein light chain 2, cytoplasmic

      See identical proteins and their annotated locations for NP_001161943.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AK006876, AL604044, AL606805
      Consensus CDS
      CCDS36272.1
      UniProtKB/Swiss-Prot
      Q9D0M5
      Related
      ENSMUSP00000136241.2, ENSMUST00000178105.3
      Conserved Domains (1) summary
      cd21452
      Location:588
      DLC-like_DYNLL1_DYNLL2; dynein light chain (DLC)-like domain found in the cytoplasmic dynein light chain 1 (DYNLL1) family
    2. NM_001168472.1NP_001161944.1  dynein light chain 2, cytoplasmic

      See identical proteins and their annotated locations for NP_001161944.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AL606805, BY249698
      Consensus CDS
      CCDS36272.1
      UniProtKB/Swiss-Prot
      Q9D0M5
      Related
      ENSMUSP00000103556.4, ENSMUST00000107923.10
      Conserved Domains (1) summary
      cd21452
      Location:588
      DLC-like_DYNLL1_DYNLL2; dynein light chain (DLC)-like domain found in the cytoplasmic dynein light chain 1 (DYNLL1) family
    3. NM_026556.4NP_080832.1  dynein light chain 2, cytoplasmic

      See identical proteins and their annotated locations for NP_080832.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AK078434, AL606805, BY310878
      Consensus CDS
      CCDS36272.1
      UniProtKB/Swiss-Prot
      Q9D0M5
      Related
      ENSMUSP00000020775.3, ENSMUST00000020775.9
      Conserved Domains (1) summary
      cd21452
      Location:588
      DLC-like_DYNLL1_DYNLL2; dynein light chain (DLC)-like domain found in the cytoplasmic dynein light chain 1 (DYNLL1) family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      87870351..87892746 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030246257.2XP_030102117.1  dynein light chain 2, cytoplasmic isoform X1

      Conserved Domains (1) summary
      cd21452
      Location:588
      DLC-like_DYNLL1_DYNLL2; dynein light chain (DLC)-like domain found in the cytoplasmic dynein light chain 1 (DYNLL1) family
    Support Center