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    Pak1ip1 PAK1 interacting protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 68083, updated on 5-Aug-2018

    Summary

    Official Symbol
    Pak1ip1provided by MGI
    Official Full Name
    PAK1 interacting protein 1provided by MGI
    Primary source
    MGI:MGI:1915333
    See related
    Ensembl:ENSMUSG00000038683 Vega:OTTMUSG00000037930
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PIP1; Gdpd1; AA419825; AI314040; AW556169; 5830431I15Rik; 5930415H02Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 48.3), adrenal adult (RPKM 35.2) and 28 other tissues See more
    Orthologs

    Genomic context

    See Pak1ip1 in Genome Data Viewer
    Location:
    13; 13 A3.3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (41001010..41013033)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (41096379..41108402)

    Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene glucosaminyl (N-acetyl) transferase 2, I-branching enzyme Neighboring gene predicted gene, 31683 Neighboring gene RIKEN cDNA A730081D07 gene Neighboring gene transmembrane protein 14C Neighboring gene male germ cell-associated kinase

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Chemically induced (ENU) (1)  1 citation
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC151106, MGC151108

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    cell proliferation IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    negative regulation of signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of signal transduction by p53 class mediator ISO
    Inferred from Sequence Orthology
    more info
     
    ribosomal large subunit biogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    roof of mouth development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    p21-activated protein kinase-interacting protein 1
    Names
    glycerophosphodiester phosphodiesterase domain containing 1
    putative PAK inhibitor Skb15

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026550.3NP_080826.2  p21-activated protein kinase-interacting protein 1

      See identical proteins and their annotated locations for NP_080826.2

      Status: VALIDATED

      Source sequence(s)
      AK150919, AV225950, BY055321, BY788898
      Consensus CDS
      CCDS36638.1
      UniProtKB/Swiss-Prot
      Q9DCE5
      Related
      ENSMUSP00000040846.9, OTTMUSP00000054841, ENSMUST00000046951.9, OTTMUST00000097774
      Conserved Domains (3) summary
      COG2319
      Location:3282
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:86121
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:28274
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

      Range
      41001010..41013033
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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