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    Dusp19 dual specificity phosphatase 19 [ Mus musculus (house mouse) ]

    Gene ID: 68082, updated on 23-Jun-2021

    Summary

    Official Symbol
    Dusp19provided by MGI
    Official Full Name
    dual specificity phosphatase 19provided by MGI
    Primary source
    MGI:MGI:1915332
    See related
    Ensembl:ENSMUSG00000027001
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SK; TS-D; SKRP1; C79103; TS-DSP1; 5930436K22Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 4.8), testis adult (RPKM 4.7) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Dusp19 in Genome Data Viewer
    Location:
    2; 2 C3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (80447558..80462005)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (80617214..80631661)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (80457371..80471818)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene NCK-associated protein 1 Neighboring gene predicted gene, 24461 Neighboring gene predicted gene 13688 Neighboring gene microRNA 684-1 Neighboring gene SMT3 suppressor of mif two 3 homolog 2 pseudogene Neighboring gene nucleoporin 35 Neighboring gene predicted gene, 36282 Neighboring gene predicted gene, 25420

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    General gene information

    Markers

    Potential readthrough

    Included gene: Nup35

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables JUN kinase phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables JUN kinase phosphatase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables MAP-kinase scaffold activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables mitogen-activated protein kinase kinase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables mitogen-activated protein kinase kinase kinase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphoprotein phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase activator activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein kinase inhibitor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein serine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein tyrosine/serine/threonine phosphatase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein tyrosine/threonine phosphatase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    dual specificity protein phosphatase 19
    Names
    protein phosphatase SKRP1
    stress-activated protein kinase pathway-regulating phosphatase 1
    NP_077758.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024438.4NP_077758.1  dual specificity protein phosphatase 19

      See identical proteins and their annotated locations for NP_077758.1

      Status: PROVISIONAL

      Source sequence(s)
      AL928869
      Consensus CDS
      CCDS16178.1
      UniProtKB/TrEMBL
      Q99N12
      Related
      ENSMUSP00000028384.5, ENSMUST00000028384.5
      Conserved Domains (1) summary
      cd00127
      Location:64200
      DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      80447558..80462005
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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