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    Mrnip MRN complex interacting protein [ Mus musculus (house mouse) ]

    Gene ID: 68067, updated on 23-Nov-2023


    Official Symbol
    Mrnipprovided by MGI
    Official Full Name
    MRN complex interacting proteinprovided by MGI
    Primary source
    See related
    Ensembl:ENSMUSG00000020381 AllianceGenome:MGI:1915317
    Gene type
    protein coding
    RefSeq status
    Mus musculus
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2900016G09Rik; 3010026O09Rik
    Predicted to enable chromatin binding activity. Predicted to be involved in several processes, including mitotic G2 DNA damage checkpoint signaling; regulation of double-strand break repair; and response to ionizing radiation. Predicted to act upstream of or within DNA repair. Predicted to be located in nucleoplasm. Predicted to be part of Mre11 complex. Predicted to be active in nucleus. Orthologous to human MRNIP (MRN complex interacting protein). [provided by Alliance of Genome Resources, Apr 2022]
    Ubiquitous expression in testis adult (RPKM 3.7), placenta adult (RPKM 3.2) and 25 other tissues See more
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    Genomic context

    See Mrnip in Genome Data Viewer
    11 B1.3; 11 30.33 cM
    Exon count:
    Annotation release Status Assembly Chr Location
    RS_2023_04 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (50065678..50090943)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (50174851..50200116)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene Neighboring gene TBC1 domain family, member 9B Neighboring gene predicted gene, 53700 Neighboring gene sequestosome 1 Neighboring gene predicted gene, 36556

    Genomic regions, transcripts, and products


    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a



    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    • Endonuclease-mediated (1)  1 citation

    General gene information


    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    enables chromatin binding ISO
    Inferred from Sequence Orthology
    more info
    Component Evidence Code Pubs
    part_of Mre11 complex ISO
    Inferred from Sequence Orthology
    more info
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info

    General protein information

    Preferred Names
    MRN complex-interacting protein
    MRN-interacting protein
    UPF0544 protein C5orf45 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026543.3NP_080819.2  MRN complex-interacting protein

      See identical proteins and their annotated locations for NP_080819.2

      Status: VALIDATED

      Source sequence(s)
      AK019392, BC028428
      Consensus CDS
      Q9CX85, Q9D1F5
      ENSMUSP00000020647.4, ENSMUST00000020647.10
      Conserved Domains (1) summary
      UPF0544; uncharacterized protein family UPF0544

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2023_04

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J


    1. NC_000077.7 Reference GRCm39 C57BL/6J

      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006534037.5XP_006534100.1  MRN complex-interacting protein isoform X1