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    Mrnip MRN complex interacting protein [ Mus musculus (house mouse) ]

    Gene ID: 68067, updated on 31-Jan-2019

    Summary

    Official Symbol
    Mrnipprovided by MGI
    Official Full Name
    MRN complex interacting proteinprovided by MGI
    Primary source
    MGI:MGI:1915317
    See related
    Ensembl:ENSMUSG00000020381
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI851514; AW475975; 2900016G09Rik; 3010026O09Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 3.7), placenta adult (RPKM 3.2) and 25 other tissues See more
    Orthologs

    Genomic context

    See Mrnip in Genome Data Viewer
    Location:
    11; 11 B1.3
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (50174851..50200116)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (49988353..50013617)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene Neighboring gene TBC1 domain family, member 9B Neighboring gene sequestosome 1 Neighboring gene predicted gene, 36556

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    chromatin binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to DNA damage stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    mitotic G2 DNA damage checkpoint ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of double-strand break repair via homologous recombination ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein localization to chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of double-strand break repair via nonhomologous end joining ISO
    Inferred from Sequence Orthology
    more info
     
    response to ionizing radiation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    colocalizes_with Mre11 complex ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    MRN complex-interacting protein; UPF0544 protein C5orf45 homolog
    Names
    MRN-interacting protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026543.3NP_080819.2  MRN complex-interacting protein

      See identical proteins and their annotated locations for NP_080819.2

      Status: VALIDATED

      Source sequence(s)
      AK019392, BC028428
      Consensus CDS
      CCDS48784.1
      UniProtKB/Swiss-Prot
      Q9D1F5
      Related
      ENSMUSP00000020647.3, ENSMUST00000020647.9
      Conserved Domains (1) summary
      pfam15749
      Location:9107
      UPF0544; uncharacterized protein family UPF0544

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      50174851..50200116
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006534037.3XP_006534100.1  UPF0544 protein C5orf45 homolog isoform X1

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